SCHEMBL5485948

SCHEMBL5485948

CCCCN(CCCC)c1ccc(C(c2ccc(N(C)CCC#N)cc2)(c2ccc(N(CCCC)CCCC)cc2)c2ccc(N(CCCC)CCCC)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 1/20 0.39
MAPT P10636 2/20 0.38
NR1H2 P55055 10/20 0.37
NR1H3 Q13133 10/20 0.37
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KDM4E B2RXH2 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
SLC16A3 O15427 1/20 0.35
SLC16A1 P53985 1/20 0.35
NR1I2 O75469 1/20 0.34
GRK6 P43250 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27609979 0.84 CRHR1 (0.39) CRHR1MAPTNR1H2NR1H3MEN1
SCHEMBL3204526 0.83 CRHR1 (0.39) CRHR1MAPTMEN1NPC1ALDH1A1
SCHEMBL5485945 0.79 GAA (0.38) NR1H2NR1H3ALDH1A1SLC16A3SLC16A1
SCHEMBL14112768 0.79 ALDH1A1 (0.42) MAPTMEN1NPC1ALDH1A1RAB9A
SCHEMBL7452206 0.75 CYP3A4 (0.47) CRHR1MAPTMEN1ALDH1A1KMT2A
SCHEMBL6553722 0.74 CRHR1 (0.41) CRHR1MAPTMEN1ALDH1A1KMT2A
SCHEMBL9323694 0.74 HSD17B10 (0.44) CRHR1MAPTNR1H2NR1H3MEN1
SCHEMBL5283357 0.73 NR1H2 (0.47) NR1H2NR1H3NR1I2
SCHEMBL12714225 0.73 MAPT (0.54) MAPTNR1H2NR1H3ALDH1A1KDM4E
SCHEMBL10336985 0.72 NR1H2 (0.39) NR1H2NR1H3SLC16A3SLC16A1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7303856-B2 Light-sensitive sheet comprising support, first light-sensitive layer and second light-sensitive layer FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed
US-7150955-B2 Light-sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. (JP) 2006-12-19 US disclosed
US-20050037281-A1 Light-sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. 2005-02-17 US disclosed
EP-1507171-A2 Light-Sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. (JP) 2005-02-16 EP disclosed
US-20050025946-A1 Light-sensitive sheet comprising support, first light-sensitive layer and second light-sensitive layer FUJI PHOTO FILM CO., LTD. 2005-02-03 US disclosed
EP-1489460-A2 Light-sensitive sheet comprising support, first light-sensitive layer and second light-sensitive layer Fuji Photo Film Co., Ltd. (JP) 2004-12-22 EP disclosed