Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614292 | 0.80 | ESR1 (0.42) | ADRB2CYP2D6CYP3A4CYP2C19BLM | |
| SCHEMBL5494557 | 0.78 | HTT (0.42) | CYP3A4CYP2C19ALDH1A1TSHRIDO1 | |
| SCHEMBL5488485 | 0.78 | CYP3A4 (0.41) | HIF1ACYP3A4CYP2C19ALDH1A1TSHR | |
| SCHEMBL11839515 | 0.77 | TSHR (0.33) | ALDH1A1TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5488086 | 0.77 | TSHR (0.37) | CYP2D6CYP3A4ALDH1A1LMNATSHR | |
| SCHEMBL3789761 | 0.77 | TSHR (0.59) | ADRB2ADRB1NISCHAOC3CYP2D6 | |
| SCHEMBL19518928 | 0.77 | TSHR (0.59) | ADRB2ADRB1NISCHAOC3CYP2D6 | |
| SCHEMBL6678856 | 0.77 | ADRB2 (0.47) | ADRB2ADRB1NISCHAOC3CYP2D6 | |
| SCHEMBL17790152 | 0.77 | TSHR (0.59) | ADRB2ADRB1NISCHAOC3CYP2D6 | |
| SCHEMBL8505733 | 0.77 | ADRB2 (0.39) | ADRB2ADRB1NISCHAOC3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |
| US-5527938-A | FRIEDEL-CRAFT ALKYLATION OF AROMATIC COMPOUNDS WITH ALLYLCHLOROSILANES USING LEWIS ACID CATALYST | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1996-06-18 | — | — | US | disclosed |