Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7614292 | 0.78 | ESR1 (0.42) | CYP2C19CYP3A4TSHRCYP2C9MAOA | |
| SCHEMBL5486163 | 0.78 | ADRB2 (0.43) | CYP2C19ALDH1A1CYP3A4TSHRCYP2C9 | |
| SCHEMBL6680371 | 0.78 | HTT (0.50) | HTTCYP2C19ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL5488485 | 0.77 | CYP3A4 (0.41) | CYP2C19ALDH1A1CYP3A4TSHRCYP2C9 | |
| SCHEMBL5488086 | 0.76 | TSHR (0.37) | HTTALDH1A1CYP3A4TSHR | |
| SCHEMBL11839515 | 0.76 | TSHR (0.33) | ALDH1A1TSHR | |
| SCHEMBL3708329 | 0.75 | TSHR (0.59) | HTTCYP2C19ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL29573338 | 0.75 | TSHR (0.59) | HTTCYP2C19ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL10456467 | 0.75 | HTT (0.43) | HTTCYP2C19ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL5487395 | 0.74 | CYP2A6 (0.36) | HTTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |