Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2826206 | 0.98 | ADORA2B (0.44) | ADORA2BPTGS1PTGS2MGLLFAAH | |
| SCHEMBL1723957 | 0.94 | ADORA2A (0.43) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL22944867 | 0.86 | — | — | |
| SCHEMBL16325249 | 0.79 | SLC9A1 (0.38) | ADORA2BPTGS1PTGS2MGLLFAAH | |
| SCHEMBL18713930 | 0.78 | SLC9A1 (0.39) | ADORA2BPTGS1PTGS2MGLLFAAH | |
| SCHEMBL31330275 | 0.77 | ADORA2A (0.31) | ADORA2BADORA2A | |
| SCHEMBL31330320 | 0.75 | ADORA3 (0.32) | ADORA2BADORA3 | |
| SCHEMBL6268666 | 0.75 | PDE3A (0.47) | PTGS1PTGS2MGLLFAAHCYP1A2 | |
| SCHEMBL31330313 | 0.74 | ADORA2A (0.33) | ADORA2BADORA2AALDH1A1 | |
| SCHEMBL31330327 | 0.74 | ADORA2A (0.33) | ADORA2BPDE4AADORA2APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831705-B1 | N-ARYL-1,2,4-TRIAZOLIN-5-ONES | BAYER AG (DE) | 2001-08-29 | — | — | EP | claimed |
| EP-0942907-A1 | 2R, 4S, S, R- AND 2S, 4R, S, R-HYDROXYITRACONAZOLE | SEPRACOR, INC. (US) | 1999-09-22 | — | — | EP | claimed |
| EP-0938484-A1 | 2R,4S,R,R- AND 2S,4R,R,R-HYDROXYITRACONAZOLE | SEPRACOR, INC. (US) | 1999-09-01 | — | — | EP | claimed |
| EP-0938487-A2 | 2$i(R),4$i(S),$i(R),$i(S)- AND 2$i(S),4$i(R),$i(R),$i(S)-HYDROXYITRACONAZOLE- AND HYDROXYSAPERCONAZOLE DERIVATIVES | SEPRACOR, INC. (US) | 1999-09-01 | — | — | EP | claimed |
| EP-0937071-A1 | 2R,4S,S,S- AND 2S,4R,S,S-HYDROXYITRACONAZOLE | SEPRACOR, INC. (US) | 1999-08-25 | — | — | EP | claimed |
| WO-1998021213-A2 | 2R,4S,R,S- AND 2S,4R,R,S-HYDROXYITRACONAZOLE- AND HYDROXYSAPERCONAZOLE DERIVATIVES | SEPRACOR, INC. (US) | 1998-05-22 | — | — | WO | claimed |
| WO-1998021205-A1 | 2R,4S,R,R- AND 2S,4R,R,R-HYDROXYITRACONAZOLE | SEPRACOR, INC. (US) | 1998-05-22 | — | — | WO | claimed |
| WO-1998021204-A1 | 2R,4S,S,S- AND 2S,4R,S,S-HYDROXYITRACONAZOLE | SEPRACOR, INC. (US) | 1998-05-22 | — | — | WO | claimed |
| WO-1998021203-A1 | 2R,4S,S,R- AND 2S,4R,S,R-HYDROXYITRACONAZOLE | SEPRACOR, INC. (US) | 1998-05-22 | — | — | WO | claimed |
| EP-0831705-A1 | N-ARYL-1,2,4-TRIAZOLIN-5-ONES | BAYER AG (DE) | 1998-04-01 | — | — | EP | claimed |
| WO-1996041535-A1 | N-ARYL-1,2,4-TRIAZOLIN-5-ONES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-27 | — | — | WO | claimed |
| EP-0221083-A1 | HALOALKYL TRIAZOLINONES | FMC Corporation (US) | 1987-05-13 | — | — | EP | claimed |
| WO-1986004481-A2 | HALOALKYL TRIAZOLINONES | FMC CORPORATION (US) | 1986-08-14 | — | — | WO | claimed |
| WO-2024249959-A1 | COMPOSITIONS REDUCING THE EXPRESSION OR ACTIVITY OF C1 GALT1 FOR TREATING EWING SARCOMA | UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL (US) | 2024-12-05 | — | — | WO | disclosed |
| US-9981940-B2 | Aryl sulfide derivatives and aryl sulfoxide derivatives as acaricides and insecticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-05-29 | — | — | US | disclosed |
| CN-104672157-B | A kind of preparation method of aryltriazolinones | 山东潍坊润丰化工股份有限公司 | 2017-06-27 | — | — | CN | disclosed |
| EP-0221083-A1 | HALOALKYL TRIAZOLINONES | FMC Corporation (US) | 1987-05-13 | — | — | EP | disclosed |
| EP-0221083-A1 | HALOALKYL TRIAZOLINONES | FMC Corporation (US) | 1987-05-13 | — | — | EP | disclosed |
| WO-1986004481-A2 | HALOALKYL TRIAZOLINONES | FMC CORPORATION (US) | 1986-08-14 | — | — | WO | disclosed |
| WO-1986004481-A2 | HALOALKYL TRIAZOLINONES | FMC CORPORATION (US) | 1986-08-14 | — | — | WO | disclosed |