Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.44 |
| ▸ | SMO | Q99835 | 7/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487370 | 0.88 | MAPK14 (0.44) | MAPK14SMOKCNH2NR1H4 | |
| SCHEMBL4417279 | 0.88 | MAPT (0.41) | MAPK14SMO | |
| SCHEMBL2842154 | 0.87 | MAPK14 (0.45) | MAPK14SMO | |
| SCHEMBL14534467 | 0.86 | NR1H4 (0.49) | MAPK14SMOKCNH2NR1H4 | |
| SCHEMBL4417658 | 0.81 | MAPT (0.42) | MAPK14SMOKCNH2 | |
| SCHEMBL4410077 | 0.81 | MAPK14 (0.43) | MAPK14SMOKCNH2NR1H4 | |
| SCHEMBL4410752 | 0.78 | NPC1 (0.46) | MAPK14 | |
| SCHEMBL4416273 | 0.78 | MAPK14 (0.41) | MAPK14SMO | |
| SCHEMBL4408412 | 0.78 | MAPK14 (0.44) | MAPK14SMOKCNH2 | |
| SCHEMBL5496963 | 0.77 | MAPK14 (0.44) | MAPK14SMOKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |