Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 11/20 | 0.41 |
| ▸ | GSK3A | P49840 | 6/20 | 0.41 |
| ▸ | SRC | P12931 | 5/20 | 0.41 |
| ▸ | SYK | P43405 | 5/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4417658 | 0.90 | MAPT (0.42) | MAPK14GSK3ASRCSYKMAPT | |
| SCHEMBL2842154 | 0.90 | MAPK14 (0.45) | MAPK14GSK3ASRCSYKLCK | |
| SCHEMBL4417851 | 0.88 | MAPK14 (0.44) | MAPK14GSK3ASRCSYKLCK | |
| SCHEMBL5490019 | 0.88 | RAB9A (0.42) | MAPK14GSK3AMAPTTRPV1 | |
| SCHEMBL4416963 | 0.88 | MAPK14 (0.44) | MAPK14GSK3ASRCSYKLCK | |
| SCHEMBL4408299 | 0.87 | MAPK14 (0.42) | MAPK14GSK3ASRCSYKLCK | |
| SCHEMBL4407832 | 0.86 | MEN1 (0.47) | MAPK14MAPTTP53TRPV1RXFP1 | |
| SCHEMBL4417279 | 0.85 | MAPT (0.41) | MAPK14MAPTTP53TRPV1RXFP1 | |
| SCHEMBL4410922 | 0.84 | MAPT (0.49) | MAPK14MAPTTP53RXFP1SMO | |
| SCHEMBL5487370 | 0.82 | MAPK14 (0.44) | MAPK14GSK3ASMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035005-A2 | THERAPY USING CYTOKINE INHIBITORS | Kemia, INC. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146712-A2 | THERAPY USING CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |