Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 12/20 | 0.44 |
| ▸ | SMO | Q99835 | 10/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408412 | 0.93 | MAPK14 (0.44) | MAPK14SMOPOLBMAPTSMN1; SMN2 | |
| SCHEMBL4408195 | 0.93 | PARP10 (0.48) | MAPK14SMOPOLBMAPTSMN1; SMN2 | |
| SCHEMBL14534669 | 0.91 | MAPK14 (0.44) | MAPK14SMOPOLBMAPTSMN1; SMN2 | |
| SCHEMBL4416216 | 0.91 | MAPK14 (0.53) | MAPK14SMOMAPTKCNH2 | |
| SCHEMBL4410077 | 0.90 | MAPK14 (0.43) | MAPK14SMOPOLBMAPTSMN1; SMN2 | |
| SCHEMBL14534691 | 0.86 | PARP10 (0.45) | MAPK14SMOPOLBMAPTSMN1; SMN2 | |
| SCHEMBL4413435 | 0.86 | MAPK14 (0.47) | MAPK14POLBMAPTSMN1; SMN2 | |
| SCHEMBL4410922 | 0.84 | MAPT (0.49) | MAPK14SMOPOLBMAPTSMN1; SMN2 | |
| SCHEMBL4417658 | 0.82 | MAPT (0.42) | MAPK14SMOMAPTSMN1; SMN2KCNH2 | |
| SCHEMBL4417279 | 0.81 | MAPT (0.41) | MAPK14SMOMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |