SCHEMBL5486514

SCHEMBL5486514

[c]1c2[c]c3ccccc3[c]c2[c]c2ccccc12

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
KDM4E B2RXH2 1/20 0.35
NPC1 O15118 1/20 0.35
CA12 O43570 1/20 0.35
GMNN O75496 1/20 0.35
EGFR P00533 1/20 0.35
CA2 P00918 1/20 0.35
LMNA P02545 1/20 0.35
FYN P06241 1/20 0.35
POLB P06746 1/20 0.35
CA3 P07451 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
MMP9 P14780 1/20 0.35
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
NFKB1 P19838 1/20 0.35
CA4 P22748 1/20 0.35
APEX1 P27695 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70153 0.84 CYP2A6 (0.36) ALDH1A1TDP1KDM4ENPC1CA12
SCHEMBL3434527 0.72 CA12 (0.39) ALDH1A1TDP1KDM4ENPC1CA12
SCHEMBL6048372 0.72 ACHE (0.39) ALDH1A1CA2LMNAALOX12
SCHEMBL508847 0.67 CYP2A6 (0.39) ALDH1A1TDP1KDM4ECA2CYP3A4
SCHEMBL17063470 0.67 HPRT1 (0.35) ALDH1A1TDP1HPGDHSD17B10CYP2A6
SCHEMBL24252 0.62 CYP2A6 (0.41) ALDH1A1TDP1KDM4ECA2CYP3A4
SCHEMBL6759020 0.62 CYP2A6 (0.33) ALDH1A1TDP1HSD17B10CYP2A6IDO1
SCHEMBL184780 0.61 ALDH1A1 (0.32) ALDH1A1CYP2A6ALOX12
SCHEMBL617580 0.59 ALDH1A1 (0.53) ALDH1A1TDP1NPC1LMNACYP3A4
SCHEMBL56536 0.59 MAPT (0.32) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0569037-B1 A reversible electrode MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1999-10-20 EP claimed
US-20070202354-A1 Organic Electroluminescent Device IDEMITSU KOSAN CO.,LTD (JP) 2007-08-30 US disclosed
EP-1737277-A1 ORGANIC ELECTROLUMINESCENT DEVICE Idemitsu Kosan Co., Ltd. (JP) 2006-12-27 EP disclosed
US-6203933-B1 ELECTROLUMINESCENT ELEMENT WITH LIGHT EMITTER LAYER AND HOLE INJECTING AND TRANSPORTATING COMPOUND TDK CORPORATION (JP) 2001-03-20 US disclosed
EP-0569037-B1 A reversible electrode MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1999-10-20 EP disclosed
EP-0939757-A1 NOVEL INTEGRIN RECEPTOR ANTAGONISTS Dupont Pharmaceuticals Company (US) 1999-09-08 EP disclosed
WO-1997023480-A1 NOVEL INTEGRIN RECEPTOR ANTAGONISTS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1997-07-03 WO disclosed