SCHEMBL548665

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL548659	0.84	KMT2A (0.46)	HSD17B10NR4A1NR4A2NR4A3PTPN1
	SCHEMBL2834703	0.79	HSD17B10 (0.75)	HSD17B10NR4A1NR4A2NR4A3PTPN1
	SCHEMBL547833	0.78	ERN1 (0.37)	HSD17B10NR4A1NR4A2NR4A3ALDH1A1
	SCHEMBL548054	0.77	ALDH1A1 (0.48)	HSD17B10ALDH1A1KMT2AMEN1KDM4E
	Ammonia Solution, Strong SCHEMBL31590375	0.77	HSD17B10 (0.72)	HSD17B10NR4A1NR4A2NR4A3PTPN1
	Hydrochloric Acid SCHEMBL4607898	0.77	HSD17B10 (0.72)	HSD17B10NR4A1NR4A2NR4A3PTPN1
	Ammonia Solution, Strong SCHEMBL31590816	0.77	HSD17B10 (0.72)	HSD17B10NR4A1NR4A2NR4A3PTPN1
	SCHEMBL29953603	0.77	HSD17B10 (0.56)	HSD17B10NR4A1NR4A2NR4A3PTPN1
	SCHEMBL547987	0.76	KMT2A (0.43)	HSD17B10NR4A1NR4A2NR4A3ALDH1A1
	SCHEMBL547832	0.76	ERN1 (0.38)	HSD17B10NR4A1NR4A2NR4A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.