SCHEMBL5486722

SCHEMBL5486722

C=Cc1[c]cccc1-c1ccsc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.39
CYP2B6 P20813 2/20 0.39
CYP2E1 P05181 1/20 0.39
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
PTPRC P08575 1/20 0.36
KCNH2 Q12809 1/20 0.34
TDO2 P48775 1/20 0.34
MAOB P27338 1/20 0.33
ENPP1 P22413 1/20 0.33
PELI1 Q96FA3 2/20 0.33
TMIGD3 P0DMS9 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31
PRKDC P78527 2/20 0.31
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2428952 0.77 ALDH1A1 (0.37) CYP2A6
SCHEMBL28320119 0.74 CYP2A6 (0.47) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL11729276 0.74 CYP2A6 (0.42) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL8878381 0.74 CYP2A6 (0.42) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL5489984 0.74 CYP2A6 (0.38) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL4946960 0.71 CYP2A6 (0.64) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL8205927 0.70 CYP2A6 (0.39) CYP2A6CYP2B6CYP2E1CYP3A4CYP2C9
SCHEMBL5495085 0.70 IMPDH2 (0.36) CYP3A4CYP2C19PELI1ADRA1DADRA1A
SCHEMBL9408188 0.70 PDPK1 (0.43) CYP2A6ADORA2AADORA1ADRA1DADRA1A
SCHEMBL9594464 0.69 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7303856-B2 Light-sensitive sheet comprising support, first light-sensitive layer and second light-sensitive layer FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed
US-7150955-B2 Light-sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. (JP) 2006-12-19 US disclosed
US-20050037281-A1 Light-sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. 2005-02-17 US disclosed
EP-1507171-A2 Light-Sensitive sheet comprising support, first and second light-sensitive layers and barrier layer FUJI PHOTO FILM CO., LTD. (JP) 2005-02-16 EP disclosed
US-20050025946-A1 Light-sensitive sheet comprising support, first light-sensitive layer and second light-sensitive layer FUJI PHOTO FILM CO., LTD. 2005-02-03 US disclosed
EP-1489460-A2 Light-sensitive sheet comprising support, first light-sensitive layer and second light-sensitive layer Fuji Photo Film Co., Ltd. (JP) 2004-12-22 EP disclosed