Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18291028 | 0.79 | ALDH1A1 (0.37) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL9594464 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HSD17B10MAPK1 | |
| SCHEMBL10971886 | 0.79 | ALDH1A1 (0.32) | ALDH1A1TSHRCASP3SENP8SENP7 | |
| SCHEMBL5486722 | 0.77 | CYP2A6 (0.39) | CYP2A6 | |
| SCHEMBL5495085 | 0.76 | IMPDH2 (0.36) | ALDH1A1HSD17B10HPGD | |
| SCHEMBL2646186 | 0.74 | KDM4E (0.42) | ALDH1A1HSD17B10HPGDMAPK1TDP1 | |
| SCHEMBL1469835 | 0.73 | ADRB2 (0.36) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL185890 | 0.71 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HPGDBCL2L1CYP2A6 | |
| SCHEMBL771645 | 0.71 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL16954840 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740540-A1 | PHENYL ACETAMIDES | Bayer HealthCare AG (DE) | 2007-01-10 | — | — | EP | claimed |
| WO-2005103001-A1 | PHENYL ACETAMIDES | BAYER HEALTHCARE AG (DE) | 2005-11-03 | — | — | WO | claimed |
| EP-1546284-B1 | REACTIVE DENDRIMERS | UNIV OXFORD INNOVATION LTD (GB) | 2018-04-04 | — | — | EP | disclosed |
| US-8025988-B2 | Reactive organometallic dendrimers | ISIS INNOVATION LIMITED (GB) | 2011-09-27 | — | — | US | disclosed |
| US-20100228022-A1 | Reactive Organometallic Dendrimers | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2010-09-09 | — | — | US | disclosed |
| US-7740954-B2 | Reactive dendrimers | ISIS INNOVATION LIMITED (GB) | 2010-06-22 | — | — | US | disclosed |
| EP-1740540-A1 | PHENYL ACETAMIDES | Bayer HealthCare AG (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005103001-A1 | PHENYL ACETAMIDES | BAYER HEALTHCARE AG (DE) | 2005-11-03 | — | — | WO | disclosed |
| EP-1572628-A1 | ISOPHTALIC ACID DERIVATIVES | Bayer HealthCare AG (DE) | 2005-09-14 | — | — | EP | disclosed |
| US-20050164029-A1 | Reactive dendrimers | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2005-07-28 | — | — | US | disclosed |
| WO-2004052839-A1 | ISOPHTALIC ACID DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-06-24 | — | — | WO | disclosed |
| US-6258506-B1 | USING BLEND OF BENZOIN ETHER AND FREE RADICAL POLYMERIZABLE SILICONE POLYMER | DOW CORNING ASIA, LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| US-6051625-A | Ultraviolet-curable polysiloxane composition and method for the formation of cured patterns therefrom | DOW CORNING ASIA, LTD. (JP) | 2000-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228022-A1 | Reactive Organometallic Dendrimers | ITGAM, CD40LG, DBN1 | ALDH1A1 933/4885HSD17B10 1741/4885HPGD 545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.