Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | GRM8 | O00222 | 2/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.44 |
| ▸ | FBP1 | P09467 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | PTPRA | P18433 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28409353 | 0.81 | GRM8 (0.52) | CYP1A2TSHRGRM8GRM4 | |
| SCHEMBL28409355 | 0.81 | GRM8 (0.52) | CYP1A2TSHRGRM8GRM4 | |
| SCHEMBL10668707 | 0.81 | ALDH1A1 (0.51) | CYP1A2TSHRL3MBTL1MEN1KMT2A | |
| SCHEMBL258742 | 0.81 | ALDH1A1 (0.51) | CYP1A2TSHRL3MBTL1MEN1KMT2A | |
| SCHEMBL258592 | 0.81 | ALDH1A1 (0.51) | CYP1A2TSHRL3MBTL1MEN1KMT2A | |
| SCHEMBL3948068 | 0.81 | ALDH1A1 (0.54) | TSHRGPR35FBP1TDP1L3MBTL1 | |
| SCHEMBL1715464 | 0.80 | L3MBTL1 (0.47) | CYP1A2TSHRTDP1L3MBTL1 | |
| SCHEMBL3535123 | 0.76 | GPR35 (0.54) | CYP1A2TSHRGPR35FBP1TDP1 | |
| SCHEMBL3722295 | 0.76 | AKR1B1 (0.47) | CYP1A2TSHRGPR35FBP1TDP1 | |
| SCHEMBL20120119 | 0.74 | SMN1; SMN2 (0.59) | TSHRTDP1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213363-A1 | Tetrahydro-Quinolinylurea Derivatives | BAYER HEALTHCARE AG (DE) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213363-A1 | Tetrahydro-Quinolinylurea Derivatives | NMUR1, OPRL1, NQO2 | CYP1A2 3234/4885TSHR 2562/4885GPR35 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.