Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.55 |
| ▸ | RAF1 | P04049 | 15/20 | 0.53 |
| ▸ | BRAF | P15056 | 15/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | BCR | P11274 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487782 | 0.78 | RAF1 (0.57) | CSF1RRAF1BRAF | |
| SCHEMBL1420016 | 0.77 | RAF1 (0.65) | CSF1RRAF1BRAFABL1BCR | |
| SCHEMBL4829508 | 0.75 | CSF1R (0.68) | CSF1RRAF1BRAF | |
| SCHEMBL22772386 | 0.74 | ABL1 (0.63) | CSF1RRAF1BRAFABL1BCR | |
| SCHEMBL3936032 | 0.74 | CSF1R (0.66) | CSF1RRAF1BRAF | |
| SCHEMBL21563869 | 0.74 | DDR1 (0.54) | CSF1RRAF1BRAF | |
| SCHEMBL25534818 | 0.72 | CSF1R (0.71) | CSF1RRAF1BRAF | |
| SCHEMBL1225981 | 0.72 | KMO (0.56) | CSF1RRAF1BRAF | |
| SCHEMBL1420492 | 0.72 | CSF1R (0.54) | CSF1RRAF1BRAF | |
| SCHEMBL27455134 | 0.72 | CSF1R (0.56) | CSF1RRAF1BRAFABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |