Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 11/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7612572 | 0.79 | ALDH1A1 (0.34) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL9417298 | 0.76 | KMT2A (0.42) | RAPGEF4CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL21120986 | 0.76 | TSHR (0.43) | RAPGEF4CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL7456451 | 0.74 | RAPGEF4 (0.39) | RAPGEF4CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL11270964 | 0.74 | CYP3A4 (0.41) | RAPGEF4CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL5488537 | 0.71 | SIRT1 (0.38) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL5484161 | 0.71 | CYP3A4 (0.42) | RAPGEF4CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL234943 | 0.71 | CYP3A4 (0.58) | RAPGEF4CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL5490607 | 0.71 | — | — | |
| SCHEMBL1314635 | 0.69 | CYP3A4 (0.55) | RAPGEF4CYP3A4CHRM1ALOX15MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |