Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 13/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21120986 | 0.79 | TSHR (0.43) | RAPGEF4CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL9417298 | 0.79 | KMT2A (0.42) | RAPGEF4CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL177502 | 0.78 | RAPGEF4 (0.33) | RAPGEF4CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL11270964 | 0.77 | CYP3A4 (0.41) | RAPGEF4CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL2290449 | 0.74 | ALDH1A1 (0.33) | RAPGEF4ALOX15ALDH1A1L3MBTL1 | |
| SCHEMBL234943 | 0.74 | CYP3A4 (0.58) | RAPGEF4CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL5488080 | 0.74 | RAPGEF4 (0.37) | RAPGEF4CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL1484477 | 0.74 | GPR35 (0.35) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL14682851 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL20577412 | 0.73 | RAPGEF4 (0.32) | RAPGEF4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775706-B1 | Borates photoinitiators from polyboranes | CIBA SC HOLDING AG (CH) | 2002-06-05 | — | — | EP | disclosed |
| EP-1203999-A2 | Photoinitiator comprising a borane and an electron donating compound | Ciba SC Holding AG (CH) | 2002-05-08 | — | — | EP | disclosed |
| US-6057078-A | PHOTOGRAPHY | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-05-02 | — | — | US | disclosed |
| US-5807905-A | POLYMERIZATION OF UNSATURATED COMPOUNDS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-09-15 | — | — | US | disclosed |
| EP-0775706-A2 | Borates photoinitiators from polyboranes | Ciba SC Holding AG (CH) | 1997-05-28 | — | — | EP | disclosed |