Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL5483037 | 0.82 | SMN1; SMN2 (0.47) | KMT2AMEN1HDAC1ALDH1A1LMNA | |
| Carbamic Acid SCHEMBL5490629 | 0.82 | SCN3A (0.61) | KMT2AKDM4ESMN1; SMN2GAAHTT | |
| SCHEMBL5489932 | 0.81 | LTA4H (0.52) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| Carbamic Acid SCHEMBL5490727 | 0.77 | KMT2A (0.53) | KMT2AMEN1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL24093122 | 0.75 | KMT2A (0.61) | KMT2AMEN1ALDH1A1LMNAHRH3 | |
| Carbamic Acid SCHEMBL5491782 | 0.75 | SCN3A (0.52) | KMT2AALDH1A1KDM4EGAAHTT | |
| Carbamic Acid SCHEMBL5487777 | 0.75 | KMT2A (0.51) | KMT2AMEN1LMNAKDM4ESMN1; SMN2 | |
| Carbamic Acid SCHEMBL5483797 | 0.75 | KMT2A (0.60) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| Carbamic Acid SCHEMBL5484597 | 0.74 | KMT2A (0.60) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| Carbamic Acid SCHEMBL5485774 | 0.74 | KMT2A (0.52) | KMT2AMEN1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687259-B1 | CYCLOPENTYL DERIVATES | NEWRON PHARM SPA (IT) | 2007-08-08 | — | — | EP | claimed |