Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095443 | 0.82 | ALDH1A1 (0.43) | LMNASMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL9881101 | 0.82 | ALDH1A1 (0.42) | LMNASMN1; SMN2HPGDTSHRMEN1 | |
| SCHEMBL28184037 | 0.79 | ALDH1A1 (0.40) | LMNASMN1; SMN2HPGDTSHRMEN1 | |
| SCHEMBL29068856 | 0.79 | MRGPRX4 (0.41) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL19983998 | 0.79 | ALDH1A1 (0.42) | LMNASMN1; SMN2HPGDMEN1KMT2A | |
| 1,2-Dichlorobenzene SCHEMBL28253435 | 0.77 | ALDH1A1 (0.55) | LMNAHPGDTSHRKMT2AALDH1A1 | |
| SCHEMBL29152933 | 0.76 | SMN1; SMN2 (0.42) | LMNASMN1; SMN2HPGDTSHRMEN1 | |
| SCHEMBL194684 | 0.76 | ALDH1A1 (0.44) | LMNASMN1; SMN2HPGDTSHRMEN1 | |
| SCHEMBL29960351 | 0.76 | ALDH1A1 (0.44) | LMNASMN1; SMN2HPGDTSHRMEN1 | |
| SCHEMBL535467 | 0.76 | LMNA (0.42) | LMNASMN1; SMN2HPGDTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1747 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506175-B1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-01 | — | — | EP | claimed |
| US-7196110-B2 | N-substituted tricyclic 3-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders | JANSSEN PHAMACEUTICA N.V. (BE) | 2007-03-27 | — | — | US | claimed |
| EP-1506175-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDGF RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-16 | — | — | EP | claimed |
| US-20040082639-A1 | N-substituted tricyclic 3-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-04-29 | — | — | US | claimed |
| WO-2003097609-A1 | N-SUBSTITUTED TRICYCLIC 3-AMINOPYRAZOLES AS PDFG RECEPTOR INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-11-27 | — | — | WO | claimed |
| EP-0354297-B1 | THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDAL AND ACARICIDAL AGENTS COMPRISING THE THIADIAZINES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-08-05 | — | — | EP | claimed |
| US-4113495-A | 2,4,4-TRIMETHYL-2-(2,5-DIHYDROXYPHENYL)-6-HYDROXY-CHROMANS | FUJI PHOTO FILM CO., LTD. (JP) | 1978-09-12 | — | — | US | claimed |
| US-3991042-A | Basic azo dyestuffs containing a benzthiazole and a tetrahydroquinoline nucleus | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-09 | — | — | US | claimed |
| US-3948877-A | POLYACRYLONITRILE, ACID MODIFIED POLYESTERS OR POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-06 | — | — | US | claimed |
| CN-118202006-A | Resin composition, cured product, optical member, ultraviolet absorber, compound, method for producing compound, and polymer | 富士胶片株式会社 | 2024-06-14 | — | — | CN | disclosed |
| CN-118176445-A | Light absorbing filter, light filter, method for manufacturing light absorbing filter, organic electroluminescent display device, inorganic electroluminescent display device, and liquid crystal display device | 富士胶片株式会社 | 2024-06-11 | — | — | CN | disclosed |
| US-11993697-B2 | Flexible tube for endoscope, endoscopic medical device, and resin composition for covering flexible tube substrate for endoscope | FUJIFILM CORPORATION (JP) | 2024-05-28 | — | — | US | disclosed |
| CN-115135643-B | Compound and organic light emitting device including the same | 株式会社LG化学 | 2024-04-30 | — | — | CN | disclosed |
| WO-2024085172-A1 | LIGHT ABSORPTION FILTER, OPTICAL FILTER AND METHOD FOR PRODUCING SAME, ORGANIC ELECTROLUMINESCENT DISPLAY DEVICE, INORGANIC ELECTROLUMINESCENT DISPLAY DEVICE, AND LIQUID CRYSTAL DISPLAY DEVICE | 富士フイルム株式会社 | 2024-04-25 | — | — | WO | disclosed |
| US-4367272-A | MORDANTS, REFLECTION | FUJI PHOTO FILM CO., LTD (JP) | 1983-01-04 | — | — | US | disclosed |
| US-4266020-A | XANTHENES AS DISCOLORATION INHIBITORS | FUJI PHOTO FILM CO., LTD. (JP) | 1981-05-05 | — | — | US | disclosed |
| US-4264720-A | CHROMENE COMPOUND COLOR STABILIZING AGENT | FUJI PHOTO FILM CO., LTD. (JP) | 1981-04-28 | — | — | US | disclosed |
| US-4259350-A | PROTECTING DEGRADABLE ORGANIC MATERIAL FROM FUNGAL OR INSECT ATTACK | SANKYO COMPANY LIMITED (JP) | 1981-03-31 | — | — | US | disclosed |
| US-4202816-A | ENOL-PIPERIDINE METAL COMPLEXES | CIBA-GEIGY CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |
| US-4113495-A | 2,4,4-TRIMETHYL-2-(2,5-DIHYDROXYPHENYL)-6-HYDROXY-CHROMANS | FUJI PHOTO FILM CO., LTD. (JP) | 1978-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082639-A1 | N-substituted tricyclic 3-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders | PDGFRA, PDGFRB, PDGFA | LMNA 2824/4885SMN1; SMN2 4012/4885HPGD 699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.