Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308547 | 0.75 | HTR2A (0.33) | — | |
| SCHEMBL6838459 | 0.74 | PBRM1 (0.39) | ALDH1A1 | |
| SCHEMBL812403 | 0.70 | SMN1; SMN2 (0.43) | GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL4433341 | 0.68 | GAA (0.40) | GAAALDH1A1 | |
| SCHEMBL8712306 | 0.68 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL1153007 | 0.67 | MAP3K14 (0.35) | GAAALDH1A1 | |
| SCHEMBL16592250 | 0.65 | PARP15 (0.30) | — | |
| SCHEMBL8086673 | 0.63 | ALDH1A1 (0.43) | GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL7142077 | 0.61 | GRIN2D (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11214884 | 0.61 | CD44 (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256158-B2 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2007-08-14 | — | — | US | disclosed |
| US-6933261-B2 | 2,4,5-Trisubstituted phenylketoenols | BAYER AKTIENGESELLSCHAFT (DE) | 2005-08-23 | — | — | US | disclosed |
| US-20050038021-A1 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | BAYER AG (DE) | 2005-02-17 | — | — | US | disclosed |
| US-20030171219-A1 | 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides | LIEB FOLKER (DE) | 2003-09-11 | — | — | US | disclosed |
| US-6511942-B1 | Animal husbandry, veterinary medicine | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-28 | — | — | US | disclosed |
| EP-0837847-B1 | 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| US-6110872-A | 3-(2,4,5-TRISUBSTITUTED PHENYL), 4-HYDROXY,5,5-(CYCLOALKYL OR HETEROCYCLOALKYL)PYRROLIN-2-ONE AND DERIVATIVES; METHOD OF MAKING BY INTRAMOLECULAR CONDENSATION OF SPECIFIED COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 2000-08-29 | — | — | US | disclosed |
| EP-0837847-A1 | 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES | BAYER AG (DE) | 1998-04-29 | — | — | EP | disclosed |
| WO-1997001535-A1 | 2,4,5-TRISUBSTITUTED PHENYLKETO-ENOLS FOR USE AS PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038021-A1 | 2,4,5,-trisubstituted phenylketo-enols for use as pesticides and herbicides | DDT, CYP4X1, PDHX | GAA 220/4885SMN1; SMN2 4600/4885GRIN2D 569/4885 |
| US-20030171219-A1 | 2,4,5-trisubstituted phenylketo-enols for use as pesticides and herbicides | DDT, CYP4X1, HPD | GAA 290/4885SMN1; SMN2 4449/4885GRIN2D 633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.