Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29463785 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3782064 | 0.92 | LMNA (0.55) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5461111 | 0.91 | L3MBTL1 (0.56) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1890195 | 0.88 | ALDH1A1 (0.52) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28601211 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14431528 | 0.87 | MEN1 (0.47) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL137848 | 0.86 | MAPT (0.52) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18524355 | 0.86 | ABL1 (0.46) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3726422 | 0.86 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1882466 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPTCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111170847-B | Novel method for preparing drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-111170847-A | Novel method for preparing drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2020-05-19 | — | — | CN | claimed |
| CN-111170847-B | Novel method for preparing drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2022-02-18 | — | — | CN | disclosed |
| CN-111170847-A | Novel method for preparing drotaverine hydrochloride intermediate | 江苏联环药业股份有限公司 | 2020-05-19 | — | — | CN | disclosed |
| US-7250410-B2 | Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses thereof | VIA PHARMACEUTICALS, INC. (US) | 2007-07-31 | — | — | US | disclosed |
| US-20040152888-A1 | Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses thereof | BAY CITY CAPITAL LLC | 2004-08-05 | — | — | US | disclosed |
| US-4442108-A | SPASMOLYTIC, HYPOTENSIVE | LABORATOIRES SOBIO S.A. OF IMMEUBLE PERISUD (FR) | 1984-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152888-A1 | Cyclic nucleotide phosphodiesterase inhibitors, preparation and uses thereof | PDE7A, PDE3B, PDE3A | ALDH1A1 395/4885MAPT 4388/4885CYP1A2 155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.