Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6925634 | 0.71 | PLA2G10 (0.48) | MEN1KMT2AMAPTNPSR1KDM4E | |
| SCHEMBL5489419 | 0.68 | NPC1 (0.46) | MEN1KMT2ACNR1CNR2KDM4E | |
| SCHEMBL5277418 | 0.67 | KDM4E (0.60) | MEN1KMT2AMAPTFOLH1CNR1 | |
| SCHEMBL25526924 | 0.63 | GPR3 (0.40) | MEN1KMT2AMAPTKDM4ECYP2C19 | |
| SCHEMBL11379297 | 0.63 | GFER (0.39) | MAPTKDM4ECYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL7049352 | 0.63 | MEN1 (0.49) | MEN1KMT2ACNR1CNR2KDM4E | |
| SCHEMBL27830151 | 0.62 | POLB (0.49) | MAPTCNR1CNR2EGFRKDM4E | |
| SCHEMBL11310708 | 0.62 | EGFR (0.49) | MEN1KMT2AMAPTEGFRKDM4E | |
| SCHEMBL12091659 | 0.62 | GPR3 (0.46) | MEN1KMT2AMAPTKDM4ECYP2C19 | |
| SCHEMBL30356335 | 0.61 | CNR1 (0.45) | KMT2AMAPTNPSR1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8974823-B2 | Solid compositions of low-solubility drugs and poloxamers | BEND RESEARCH, INC. (US) | 2015-03-10 | — | — | US | disclosed |
| US-20070141143-A1 | Solid compositions of low-solubility drugs and poloxamers | PFIZER PRODUCTS INC. | 2007-06-21 | — | — | US | disclosed |