Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 5/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5277418 | 0.78 | KDM4E (0.60) | NPC1KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL7076384 | 0.69 | MAPT (0.47) | NPC1KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL5489412 | 0.68 | MEN1 (0.41) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL25437053 | 0.68 | NPC1 (0.56) | NPC1KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL7744033 | 0.66 | F10 (0.56) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29643244 | 0.66 | NPC1 (0.80) | NPC1KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL28266234 | 0.66 | NPC1 (0.80) | NPC1KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL21822408 | 0.66 | KDM4E (0.60) | NPC1KDM4EALDH1A1HPGDLMNA | |
| SCHEMBL27361847 | 0.66 | KDM4E (0.62) | NPC1KDM4EALDH1A1CNR2CNR1 | |
| SCHEMBL27507950 | 0.66 | NPC1 (0.56) | NPC1KDM4EALDH1A1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8974823-B2 | Solid compositions of low-solubility drugs and poloxamers | BEND RESEARCH, INC. (US) | 2015-03-10 | — | — | US | disclosed |
| US-20070141143-A1 | Solid compositions of low-solubility drugs and poloxamers | PFIZER PRODUCTS INC. | 2007-06-21 | — | — | US | disclosed |