Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30999512 | 0.92 | NPC1 (0.56) | MAPTNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL12540590 | 0.87 | FAAH (0.56) | MAPTNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL12540588 | 0.87 | FAAH (0.56) | MAPTNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL28029757 | 0.80 | NPC1 (0.51) | MAPTNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL11174009 | 0.78 | XDH (0.55) | MAPTNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL11800918 | 0.77 | AURKA (0.56) | MAPTNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL10362585 | 0.76 | AURKA (0.59) | MAPTNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL27983608 | 0.76 | MAPT (0.82) | MAPTNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL11326909 | 0.75 | FAAH (0.53) | MAPTNPC1RAB9ASMN1; SMN2NPSR1 | |
| SCHEMBL11326911 | 0.75 | FAAH (0.53) | MAPTNPC1RAB9ASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045279-B1 | AMINE OXIDE COMPOUNDS, PROCESSES FOR THEIR MANUFACTURE AND THEIR USE AS OPTICAL BRIGHTENERS | CIBA-GEIGY AG (CH) | 1988-06-01 | — | — | EP | claimed |
| EP-0029003-B1 | SALTS OF CATIONIC BRIGHTENERS, THEIR PREPARATION AND THEIR USE ON ORGANIC MATERIALS AS WELL AS THEIR CONCENTRATED AQUEOUS SOLUTIONS | CIBA-GEIGY AG (CH) | 1984-12-05 | — | — | EP | claimed |
| US-4433975-A | HETEROCYCLIC QUATERNARY AMMONIUM PHOSPHATES | CIBA-GEIGY CORPORATION (US) | 1984-02-28 | — | — | US | claimed |
| US-4432886-A | 2-FURANYLBENZIMIDAZOLE, OR 2-AZOLYLBENZIMIDAZOLE, OR 2-STILBENYLBENZIMIDAZOLE, OR 2,5-(BENZIMIDAZOLYL)FURAN PHOSPHATES | CIBA-GEIGY CORPORATION (US) | 1984-02-21 | — | — | US | claimed |
| US-4384121-A | WATER SOLUBLE | CIBA-GEIGY CORPORATION (US) | 1983-05-17 | — | — | US | claimed |
| EP-0045279-A1 | Amine oxide compounds, processes for their manufacture and their use as optical brighteners | CIBA-GEIGY AG (CH) | 1982-02-03 | — | — | EP | claimed |
| EP-0029003-A2 | Salts of cationic brighteners, their preparation and their use on organic materials as well as their concentrated aqueous solutions | CIBA-GEIGY AG (CH) | 1981-05-20 | — | — | EP | claimed |
| US-20070249840-A1 | Process for the preparation of bis-benzazolyl compounds | ELIU VICTOR P | 2007-10-25 | — | — | US | disclosed |
| EP-1326850-B1 | A PROCESS FOR THE PREPARATION OF BIS-BENZAZOLYL COMPOUNDS | CIBA SC HOLDING AG (CH) | 2005-11-16 | — | — | EP | disclosed |
| US-20030191320-A1 | Process for the preparation of bis-benzazolyl compounds | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-10-09 | — | — | US | disclosed |
| EP-1326850-A1 | A PROCESS FOR THE PREPARATION OF BIS-BENZAZOLYL COMPOUNDS | Ciba SC Holding AG (CH) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032886-A1 | A PROCESS FOR THE PREPARATION OF BIS-BENZAZOLYL COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-04-25 | — | — | WO | disclosed |
| EP-0170091-B2 | Liquid detergent compositions | ALBRIGHT & WILSON (GB) | 1997-11-19 | — | — | EP | disclosed |
| EP-0151884-A2 | Liquid detergent compositions | Albright & Wilson Limited (GB) | 1985-08-21 | — | — | EP | disclosed |
| US-4515704-A | LAUNDERING | ALBRIGHT & WILSON LIMITED (GB) | 1985-05-07 | — | — | US | disclosed |
| EP-0029003-B1 | SALTS OF CATIONIC BRIGHTENERS, THEIR PREPARATION AND THEIR USE ON ORGANIC MATERIALS AS WELL AS THEIR CONCENTRATED AQUEOUS SOLUTIONS | CIBA-GEIGY AG (CH) | 1984-12-05 | — | — | EP | disclosed |
| EP-0086614-A1 | Liquid detergent compositions | Albright & Wilson Limited (GB) | 1983-08-24 | — | — | EP | disclosed |
| EP-0045279-A1 | Amine oxide compounds, processes for their manufacture and their use as optical brighteners | CIBA-GEIGY AG (CH) | 1982-02-03 | — | — | EP | disclosed |
| US-4295850-A | Commercial preparations of dry organic substances | CIBA-GEIGY CORPORATION (US) | 1981-10-20 | — | — | US | disclosed |
| EP-0029003-A2 | Salts of cationic brighteners, their preparation and their use on organic materials as well as their concentrated aqueous solutions | CIBA-GEIGY AG (CH) | 1981-05-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191320-A1 | Process for the preparation of bis-benzazolyl compounds | HBZ, HBG1, OR10J3 | MAPT 4632/4885NPC1 3706/4885RAB9A 2792/4885 |
| US-20070249840-A1 | Process for the preparation of bis-benzazolyl compounds | HBZ, H1-3, HBS1L | MAPT 4313/4885NPC1 3829/4885RAB9A 2925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.