Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410752 | 0.93 | NPC1 (0.46) | MEN1KMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL4565964 | 0.92 | MAPK14 (0.42) | BRAFMEN1KMT2ALMNAMAPT | |
| SCHEMBL4413445 | 0.92 | LMNA (0.44) | BRAFMEN1KMT2ALMNAGAA | |
| SCHEMBL4410224 | 0.90 | MAPK14 (0.43) | BRAFMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL4420870 | 0.89 | MRGPRX4 (0.43) | BRAFMEN1KMT2ALMNAGAA | |
| SCHEMBL4417279 | 0.88 | MAPT (0.41) | BRAFMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL4411102 | 0.85 | MAPK14 (0.42) | GSK3ANPC1MAPK14 | |
| SCHEMBL14534466 | 0.81 | MAPK14 (0.45) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL14534469 | 0.80 | MAPK14 (0.43) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL4409868 | 0.80 | ALDH1A1 (0.47) | MEN1KMT2ALMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |