Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | BCL9 | O00512 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.45 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2597473 | 0.88 | HTR2A (0.56) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL6819876 | 0.88 | HTR2A (0.53) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL3559196 | 0.88 | HTR2A (0.53) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL21097318 | 0.85 | HTR2A (0.54) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL21097661 | 0.85 | HTR2A (0.51) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL18757845 | 0.85 | HTR2A (0.54) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL409598 | 0.85 | HTR2A (0.59) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL2597423 | 0.84 | BCL9 (0.54) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL5526504 | 0.83 | HTR2A (0.58) | HTR2ABCL9CTNNB1GAAKMT2A | |
| SCHEMBL25565815 | 0.83 | HTR2A (0.47) | HTR2ABCL9CTNNB1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191263-A1 | Valency platform molecules comprising aminooxy groups | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2007-08-16 | — | — | US | disclosed |
| US-20060141597-A1 | A conjugate of biologically active molecules e.g peptides, proteins, nucleic acids, hormones, lipids, antibodies, saccharides, epitopes, enzymes, drugs etc. and a polyoxyethylene containing aminoxy groups | JONES DAVID S | 2006-06-29 | — | — | US | disclosed |
| US-6951939-B2 | Multivalent platform molecules comprising high molecular weight polyethylene oxide | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2005-10-04 | — | — | US | disclosed |
| US-20040224366-A1 | Valency platform molecules comprising aminooxy groups | JONES DAVID S (US) | 2004-11-11 | — | — | US | disclosed |
| US-20020110535-A1 | Multivalent platform molecules comprising high molecular weight polyethylene oxide | LA JOLLA PHARMACEUTICAL COMPANY | 2002-08-15 | — | — | US | disclosed |
| EP-1183230-A1 | VALENCY PLATFORM MOLECULES COMPRISING AMINOOXY GROUPS | LA JOLLA PHARMACEUTICAL (US) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000075105-A1 | VALENCY PLATFORM MOLECULES COMPRISING AMINOOXY GROUPS | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2000-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191263-A1 | Valency platform molecules comprising aminooxy groups | DAO, PAM, BCAT2 | HTR2A 2645/4885BCL9 2121/4885CTNNB1 3298/4885 |
| US-20020110535-A1 | Multivalent platform molecules comprising high molecular weight polyethylene oxide | TLR3, ACP1, TLR9 | HTR2A 3304/4885BCL9 1120/4885CTNNB1 4178/4885 |
| US-20060141597-A1 | A conjugate of biologically active molecules e.g peptides, proteins, nucleic acids, hormones, lipids, antibodies, saccharides, epitopes, enzymes, drugs etc. and a polyoxyethylene containing aminoxy groups | SHBG, DAO, DNPEP | HTR2A 3032/4885BCL9 1706/4885CTNNB1 4160/4885 |
| US-20040224366-A1 | Valency platform molecules comprising aminooxy groups | DAO, PAM, BCAT2 | HTR2A 2645/4885BCL9 2121/4885CTNNB1 3298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.