Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 6/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MTTP | P55157 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479999 | 0.91 | CCR3 (0.51) | HTR7HTR1ADRD2HTR6MEN1 | |
| SCHEMBL8479942 | 0.90 | CCR3 (0.51) | HTR7HTR1ADRD2HTR6MEN1 | |
| SCHEMBL8653097 | 0.87 | MTTP (0.44) | HTR7HTR1ADRD2HTR6MTTP | |
| SCHEMBL8667924 | 0.86 | CCR3 (0.48) | HTR7HTR1ADRD2HTR6MEN1 | |
| Hydrochloric Acid SCHEMBL8663914 | 0.85 | CCR3 (0.47) | HTR7HTR1ADRD2HTR6MEN1 | |
| SCHEMBL8523534 | 0.85 | ADRA1D (0.53) | MEN1KMT2AADRA1AKCNH2POLB | |
| SCHEMBL8504393 | 0.82 | CCR3 (0.43) | HTR7HTR1ADRD2HTR6MEN1 | |
| SCHEMBL8483451 | 0.82 | DRD2 (0.42) | HTR1ADRD2ALDH1A1POLBDRD4 | |
| SCHEMBL8667996 | 0.80 | UTS2R (0.47) | HTR7DRD2ADRA1ADRD4 | |
| SCHEMBL8480390 | 0.77 | HTR1A (0.48) | HTR7HTR1ACCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537073-B1 | BENZAMIDE OR PHENYLACETAMIDE DERIVATIVES USEFUL AS THYROID RECEPTOR LIGANDS | KAROBIO AB (SE) | 2007-09-12 | — | — | EP | disclosed |