Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 16/20 | 0.48 |
| ▸ | HTR7 | P34969 | 16/20 | 0.48 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523534 | 0.84 | ADRA1D (0.53) | CCR3 | |
| SCHEMBL8483451 | 0.82 | DRD2 (0.42) | HTR1A | |
| SCHEMBL8667996 | 0.81 | UTS2R (0.47) | HTR7 | |
| SCHEMBL8712879 | 0.81 | HTR1A (0.37) | HTR1AHTR7SFRP1CCR3 | |
| SCHEMBL8479999 | 0.78 | CCR3 (0.51) | HTR1AHTR7CCR3 | |
| SCHEMBL8479942 | 0.78 | CCR3 (0.51) | HTR1AHTR7CCR3 | |
| SCHEMBL8665585 | 0.78 | HRH2 (0.35) | HTR1AHTR7SFRP1CCR3HRH2 | |
| SCHEMBL5490017 | 0.77 | HTR7 (0.46) | HTR1AHTR7CCR3 | |
| SCHEMBL8653097 | 0.76 | MTTP (0.44) | HTR1AHTR7CCR3 | |
| SCHEMBL8667924 | 0.76 | CCR3 (0.48) | HTR1AHTR7CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883099-A | TREATMENT OF ATHERSCLEROSIS, PANCREATITIS OBESITY OR HYPERGLYCEMIA | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-16 | — | — | US | disclosed |