Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.44 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL403603 | 0.96 | NPSR1 (0.51) | NPSR1TAS1R3TAS1R1LMNAALDH1A1 | |
| SCHEMBL16285365 | 0.89 | NPSR1 (0.67) | NPSR1TAS1R3TAS1R1LMNAALDH1A1 | |
| SCHEMBL404773 | 0.82 | PPARG (0.48) | TAS1R3TAS1R1LMNAALDH1A1PLK1 | |
| SCHEMBL13760112 | 0.80 | TAS1R3 (0.61) | TAS1R3TAS1R1LMNAALDH1A1PLK1 | |
| SCHEMBL3218942 | 0.79 | NPSR1 (0.54) | NPSR1LMNAPPARGPPARACA2 | |
| SCHEMBL5858248 | 0.78 | TAS1R3 (0.63) | NPSR1TAS1R3TAS1R1LMNAALDH1A1 | |
| SCHEMBL3099766 | 0.78 | DGAT1 (0.61) | NPSR1MEN1KMT2AATM | |
| SCHEMBL3087393 | 0.78 | DGAT1 (0.61) | NPSR1MEN1KMT2AATM | |
| SCHEMBL14380335 | 0.77 | TAS1R3 (0.67) | TAS1R3TAS1R1LMNAALDH1A1PLK1 | |
| SCHEMBL10781729 | 0.77 | CA1 (0.55) | TAS1R3TAS1R1LMNAALDH1A1PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244197-A1 | Antibacterial agents | UNIVERSITY OF WASHINGTON (US) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244197-A1 | Antibacterial agents | MRPL21, SI, PGLS | NPSR1 2756/4885TAS1R3 4169/4885TAS1R1 3477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.