Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5487357 | 0.79 | PYCR1 (0.44) | PYCR1MAPK1ALDH1A1 | |
| SCHEMBL5490741 | 0.75 | POLB (0.34) | PYCR1MAPK1ALDH1A1 | |
| SCHEMBL11022982 | 0.75 | PYCR1 (0.43) | PYCR1ALOX15MAPK1HSP90AA1TLR9 | |
| SCHEMBL7955333 | 0.74 | ALOX15 (0.46) | PYCR1ALOX15MAPK1HSP90AA1TLR9 | |
| SCHEMBL7609506 | 0.73 | TAAR1 (0.46) | PYCR1ALDH1A1L3MBTL1TSHR | |
| SCHEMBL2789656 | 0.72 | PYCR1 (0.44) | PYCR1ALOX15MAPK1HSP90AA1TLR9 | |
| SCHEMBL9171541 | 0.70 | PYCR1 (0.43) | PYCR1ALOX15MAPK1HSP90AA1TLR9 | |
| SCHEMBL5482481 | 0.70 | CYP3A4 (0.36) | TDP1TSHRAHR | |
| SCHEMBL9171547 | 0.70 | PYCR1 (0.43) | PYCR1ALOX15MAPK1HSP90AA1TLR9 | |
| SCHEMBL28879858 | 0.70 | CYP2A6 (0.47) | PYCR1ALOX15MAPK1HSP90AA1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |