Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | CASP7 | P55210 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1799678 | 0.68 | ALDH1A1 (0.63) | ALDH1A1HSD17B10KDM4EPOLBMAPT | |
| SCHEMBL297554 | 0.65 | ALDH1A1 (0.43) | ALDH1A1HSD17B10KDM4EPOLBMAPT | |
| SCHEMBL22640 | 0.65 | ALDH1A1 (0.43) | ALDH1A1HSD17B10KDM4EPOLBMAPT | |
| SCHEMBL4015828 | 0.64 | HPGDS (0.36) | — | |
| SCHEMBL16740688 | 0.64 | POLB (0.38) | ALDH1A1HSD17B10KDM4EPOLBMAPT | |
| SCHEMBL25757 | 0.64 | — | — | |
| SCHEMBL5178832 | 0.63 | ALDH1A1 (0.38) | ALDH1A1HSD17B10KDM4EPOLBMAPT | |
| SCHEMBL630904 | 0.62 | ALDH1A1 (0.40) | ALDH1A1HSD17B10KDM4EPOLBMAPT | |
| SCHEMBL10560469 | 0.62 | ALDH1A1 (0.43) | ALDH1A1HSD17B10KDM4EMAPTMEN1 | |
| SCHEMBL15987586 | 0.61 | ALDH1A1 (0.39) | ALDH1A1HSD17B10KDM4EPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 893 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403606-A | Blue light organic semiconductor material with aromatic silicon hetero-polycyclic ring and preparation method and application thereof | 华南理工大学 | 2022-11-29 | — | — | CN | claimed |
| CN-107073066-B | mTORC1 inhibitors | 加利福尼亚大学董事会 | 2021-09-17 | — | — | CN | claimed |
| US-20170246305-A1 | mTORC1 INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-08-31 | — | — | US | claimed |
| CN-107073066-A | mTORC1 inhibitors | 加利福尼亚大学董事会 | 2017-08-18 | — | — | CN | claimed |
| EP-3193902-A1 | mTORC1 INHIBITORS | The Regents of The University of California (US) | 2017-07-26 | — | — | EP | claimed |
| WO-2016128356-A1 | LIGHT-ABSORBING COMPOUNDS | Technische Universität Dresden (DE) | 2016-08-18 | — | — | WO | claimed |
| WO-2016040806-A1 | mTORC1 INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-03-17 | — | — | WO | claimed |
| CN-104379563-A | Compositions and methods for treating cancer | UNIV CALIFORNIA | 2015-02-25 | — | — | CN | claimed |
| EP-2836482-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | The Regents of The University of California (US) | 2015-02-18 | — | — | EP | claimed |
| WO-2013155223-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-17 | — | — | WO | claimed |
| EP-0630382-B1 | LACTAM DIPEPTIDES HAVING HLE INHIBITING ACTIVITY | ZENECA LTD (GB) | 1997-02-26 | — | — | EP | claimed |
| WO-1996025398-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AND THEIR USE AS FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | claimed |
| EP-0708098-A1 | Oxime derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1996-04-24 | — | — | EP | claimed |
| EP-0359547-B1 | Pyridine compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-01-24 | — | — | EP | claimed |
| EP-0553630-A1 | Pyridyloxy-naphthalines as herbicides | BAYER AG (DE) | 1993-08-04 | — | — | EP | claimed |
| US-5093356-A | Antiallergens, antiasthma, antiinflammatory, cytoprotective | MERCK FROSST CANADA, INC. (CA) | 1992-03-03 | — | — | US | claimed |
| CN-85105298-A | 1, the preparation method of 3-dithiole-2-ylidene derivatives | — | 1987-01-28 | — | — | CN | claimed |
| EP-0067508-A1 | Amidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-22 | — | — | EP | claimed |
| US-4215118-A | BACTERICIDES, ANIMAL GROWTH PROMOTERS, PRESERVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-07-29 | — | — | US | claimed |
| US-4036812-A | ULTRAVIOLET STABILIZERS FOR POLYMERS | SANDOZ LTD. (CH) | 1977-07-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170246305-A1 | mTORC1 INHIBITORS | MTOR, RPTOR, RICTOR | ALDH1A1 4715/4885HSD17B10 2230/4885KDM4E 1643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.