Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10735 | 0.83 | — | — | |
| Piperidine SCHEMBL5490582 | 0.81 | IDO1 (0.51) | POLBNPC1MEN1KMT2ASLC6A2 | |
| Ammonia Solution, Strong SCHEMBL28623820 | 0.81 | TAAR1 (0.54) | POLBMEN1KMT2AHRH3TAAR1 | |
| Dimethylamine SCHEMBL2646042 | 0.77 | TAAR1 (0.50) | NPC1TAAR1MAP2K4DAOIDO1 | |
| Metacresol SCHEMBL27664444 | 0.77 | ACHE (0.65) | POLBHTR2CADRB1 | |
| SCHEMBL27675165 | 0.73 | S1PR1 (0.42) | POLBNPC1MEN1KMT2AHRH3 | |
| SCHEMBL8405030 | 0.72 | CTBP2 (0.55) | POLBNPC1MEN1KMT2ACTBP2 | |
| SCHEMBL14960038 | 0.72 | PRKCI (0.58) | TAAR1MAP2K4IDO1 | |
| M-Xylene SCHEMBL27949426 | 0.71 | ACHE (0.44) | POLBNPC1MEN1KMT2AHTR2C | |
| Malonic Acid SCHEMBL27771971 | 0.71 | NPC1 (0.50) | POLBNPC1MEN1KMT2ACTBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151501-A1 | Compounds having growth hormone releasing activity | BOWERS CYRIL Y (US) | 2002-10-17 | — | — | US | claimed |
| EP-1159292-A2 | COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | Administrators of The Tulane Educational Fund (US) | 2001-12-05 | — | — | EP | claimed |
| WO-2000009537-A2 | COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2000-02-24 | — | — | WO | claimed |
| US-7250399-B2 | Compounds having growth hormone releasing activity | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2007-07-31 | — | — | US | disclosed |
| US-6468974-B1 | OLIGOPEPTIDES THAT PROVIDE DESIRABLE IN VITRO AND IN VIVO GROWTH HORMONE RELEASING ACTIVITY AND HAVE AT LEAST ONE OTHER DESIRABLE BIOLOGICAL ACTIVITY SUCH AS INCREASED RETENTION TIME | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND | 2002-10-22 | — | — | US | disclosed |
| US-20020151501-A1 | Compounds having growth hormone releasing activity | BOWERS CYRIL Y (US) | 2002-10-17 | — | — | US | disclosed |
| EP-1159292-A2 | COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | Administrators of The Tulane Educational Fund (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000009537-A2 | COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2000-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151501-A1 | Compounds having growth hormone releasing activity | GHSR, GHRHR, NPY1R | POLB 2047/4885NPC1 3784/4885MEN1 237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.