Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667381 | 0.84 | IDO1 (0.69) | IDO1MAOBHRH3TAAR1MAOA | |
| Piperidine SCHEMBL5490575 | 0.81 | POLB (0.50) | IDO1HTR6POLBHTR2CHTR2B | |
| SCHEMBL9842152 | 0.80 | IDO1 (0.64) | IDO1MAOBTAAR1MAOA | |
| SCHEMBL9283193 | 0.78 | TSHR (0.62) | IDO1POLBMAOBTACR1TAAR1 | |
| Hydroquinone SCHEMBL10866249 | 0.77 | IDO1 (0.60) | IDO1MAOBTAAR1MAOA | |
| SCHEMBL12266469 | 0.77 | IDO1 (0.60) | IDO1MAOBTAAR1MAOA | |
| Metacresol SCHEMBL27664444 | 0.75 | ACHE (0.65) | POLBHTR2CADRB1 | |
| SCHEMBL8750524 | 0.74 | IDO1 (0.62) | IDO1MAOBTAAR1MAOA | |
| SCHEMBL11019394 | 0.73 | IDO1 (0.60) | IDO1MAOBTAAR1MAOA | |
| SCHEMBL3160721 | 0.73 | IDO1 (0.60) | IDO1MAOBHRH3TAAR1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151501-A1 | Compounds having growth hormone releasing activity | BOWERS CYRIL Y (US) | 2002-10-17 | — | — | US | claimed |
| EP-1159292-A2 | COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | Administrators of The Tulane Educational Fund (US) | 2001-12-05 | — | — | EP | claimed |
| WO-2000009537-A2 | COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2000-02-24 | — | — | WO | claimed |
| US-7250399-B2 | Compounds having growth hormone releasing activity | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2007-07-31 | — | — | US | disclosed |
| US-6468974-B1 | OLIGOPEPTIDES THAT PROVIDE DESIRABLE IN VITRO AND IN VIVO GROWTH HORMONE RELEASING ACTIVITY AND HAVE AT LEAST ONE OTHER DESIRABLE BIOLOGICAL ACTIVITY SUCH AS INCREASED RETENTION TIME | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND | 2002-10-22 | — | — | US | disclosed |
| US-20020151501-A1 | Compounds having growth hormone releasing activity | BOWERS CYRIL Y (US) | 2002-10-17 | — | — | US | disclosed |
| EP-1159292-A2 | COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | Administrators of The Tulane Educational Fund (US) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000009537-A2 | COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY | ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2000-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020151501-A1 | Compounds having growth hormone releasing activity | GHSR, GHRHR, NPY1R | IDO1 1831/4885HTR6 832/4885POLB 2047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.