Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1624311 | 0.79 | SMN1; SMN2 (0.51) | CYP2C19SMN1; SMN2MEN1CYP3A4CYP2C9 | |
| SCHEMBL27572033 | 0.79 | TP53 (0.54) | CYP2C19SMN1; SMN2MEN1CYP3A4CYP2C9 | |
| SCHEMBL5090319 | 0.77 | MEN1 (0.50) | CYP2C19SMN1; SMN2MEN1CYP3A4CYP2C9 | |
| SCHEMBL4312600 | 0.77 | MEN1 (0.50) | CYP2C19SMN1; SMN2MEN1CYP3A4CYP2C9 | |
| SCHEMBL9407535 | 0.77 | MEN1 (0.50) | CYP2C19SMN1; SMN2MEN1CYP3A4CYP2C9 | |
| SCHEMBL25736671 | 0.77 | MEN1 (0.50) | CYP2C19SMN1; SMN2MEN1CYP3A4CYP2C9 | |
| SCHEMBL8501723 | 0.77 | L3MBTL1 (0.59) | CYP2C19PPARGPPARASMN1; SMN2MEN1 | |
| SCHEMBL8466175 | 0.76 | TP53 (0.51) | CYP2C19SMN1; SMN2MEN1CYP3A4CYP2C9 | |
| SCHEMBL5805153 | 0.76 | SMN1; SMN2 (0.49) | CYP2C19SMN1; SMN2MEN1CYP3A4CYP2C9 | |
| SCHEMBL12750822 | 0.76 | HSD11B1 (0.40) | CYP2C19PPARGPPARASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763509-A1 | ALPHA-HELICAL MIMETICS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006002474-A1 | ALPHA-HELICAL MIMETICS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2006-01-12 | — | — | WO | disclosed |