Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 3/20 | 0.44 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490741 | 0.84 | POLB (0.34) | PYCR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5490805 | 0.79 | PYCR1 (0.40) | PYCR1ALDH1A1MAPK1 | |
| SCHEMBL5482845 | 0.78 | HDAC3 (0.40) | CYP1A2CYP2C9CYP2C19MAPK1POLB | |
| SCHEMBL29418547 | 0.77 | PYCR1 (0.47) | PYCR1KDM5AKDM4CKDM5BCYP1A2 | |
| SCHEMBL12053 | 0.77 | PYCR1 (0.47) | PYCR1KDM5AKDM4CKDM5BCYP1A2 | |
| SCHEMBL29676673 | 0.74 | PYCR1 (0.49) | PYCR1KDM5AKDM4CKDM5BMAPT | |
| SCHEMBL30169578 | 0.74 | PYCR1 (0.49) | PYCR1KDM5AKDM4CKDM5BCYP1A2 | |
| SCHEMBL307129 | 0.74 | PYCR1 (0.49) | PYCR1KDM5AKDM4CKDM5BMAPT | |
| SCHEMBL12164465 | 0.74 | PYCR1 (0.49) | PYCR1KDM5AKDM4CKDM5BCYP1A2 | |
| SCHEMBL5481506 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |