Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 4/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680297 | 0.80 | TSHR (0.50) | SLC6A4HTR2ARIPK1SLC6A2POLB | |
| SCHEMBL29960384 | 0.80 | TSHR (0.50) | SLC6A4HTR2ARIPK1SLC6A2POLB | |
| SCHEMBL9092579 | 0.77 | SLC6A4 (0.44) | SLC6A4HTR2ARIPK1SLC6A2KCNH2 | |
| SCHEMBL5488878 | 0.77 | LTA4H (0.43) | LTA4HTSHR | |
| SCHEMBL6682183 | 0.75 | SLC6A4 (0.51) | SLC6A4HTR2ARIPK1SLC6A2KCNH2 | |
| SCHEMBL5853299 | 0.74 | LTA4H (0.46) | SLC6A4HTR2ARIPK1SLC6A2POLB | |
| SCHEMBL6683659 | 0.73 | LTA4H (0.46) | SLC6A4HTR2ARIPK1SLC6A2POLB | |
| SCHEMBL6683964 | 0.72 | LTA4H (0.45) | SLC6A4HTR2APOLBLTA4HL3MBTL1 | |
| SCHEMBL5486163 | 0.72 | ADRB2 (0.43) | SLC6A4SLC6A2LMNAALDH1A1TSHR | |
| SCHEMBL2356142 | 0.72 | SLC6A4 (0.49) | SLC6A4HTR2ARIPK1SLC6A2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |