Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.65 |
| ▸ | REN | P00797 | 2/20 | 0.64 |
| ▸ | CASP3 | P42574 | 2/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.63 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.60 |
| ▸ | CASP9 | P55211 | 1/20 | 0.60 |
| ▸ | CTSB | P07858 | 5/20 | 0.55 |
| ▸ | CTSL | P07711 | 4/20 | 0.55 |
| ▸ | CTSK | P43235 | 3/20 | 0.55 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | MME | P08473 | 2/20 | 0.55 |
| ▸ | ECE1 | P42892 | 2/20 | 0.55 |
| ▸ | TACR1 | P25103 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7327620 | 0.96 | CAPN1 (0.64) | CASP1RENCASP3CASP7CAPN1 | |
| SCHEMBL13355677 | 0.94 | CAPN1 (0.67) | CASP1CAPN1CTSBCTSLCTSK | |
| SCHEMBL7204154 | 0.94 | CAPN1 (0.67) | CASP1CAPN1CTSBCTSLCTSK | |
| SCHEMBL5686620 | 0.93 | REN (0.65) | CASP1RENCASP3CASP7CAPN1 | |
| SCHEMBL31397615 | 0.89 | CAPN1 (0.72) | CAPN1CTSBCTSLCTSKCTSS | |
| SCHEMBL7281206 | 0.89 | CAPN1 (0.72) | CAPN1CTSBCTSLCTSKCTSS | |
| SCHEMBL10967811 | 0.89 | CAPN1 (0.72) | CAPN1CTSBCTSLCTSKCTSS | |
| SCHEMBL9088735 | 0.89 | CAPN1 (0.72) | CAPN1CTSBCTSLCTSKCTSS | |
| SCHEMBL5484209 | 0.89 | CAPN1 (0.72) | CAPN1CTSBCTSLCTSKCTSS | |
| SCHEMBL7888072 | 0.88 | CTSK (0.60) | CASP1RENCASP3CASP7CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7270801-B2 | Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for caspases and other enzymes and the use thereof | CYTOVIA, INC. (US) | 2007-09-18 | — | — | US | disclosed |
| EP-1026988-A4 | NOVEL FLUORESCENT REPORTER MOLECULES AND THEIR APPLICATIONS INCLUDING ASSAYS FOR CASPASES | CYTOVIA INC (US) | 2005-03-30 | — | — | EP | disclosed |
| US-20040191844-A1 | Novel fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for caspases and other enzymes and the use thereof | CYTOVIA, INC. (US) | 2004-09-30 | — | — | US | disclosed |
| US-6759207-B2 | REPORTER COMPOUND FOR USE IN THE DIAGNOSIS, DETECTION AND TREATMENT OF CANCER | CYTOVIA, INC. | 2004-07-06 | — | — | US | disclosed |
| WO-2003048198-A2 | POLYPEPTIDES INDUCING APOPTOSIS, POLYNUCLEOTIDES ENCODING THEM AND THERAPEUTIC USES THEREOF | INSTITUT PASTEUR (FR) | 2003-06-12 | — | — | WO | disclosed |
| US-20020150885-A1 | Novel fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for caspases and other enzymes and the use thereof | CYTOVIA, INC. | 2002-10-17 | — | — | US | disclosed |
| US-6342611-B1 | BLOCKED RHODAMINE DERIVATIVES | CYTOVIA, INC. | 2002-01-29 | — | — | US | disclosed |
| US-6335429-B1 | COMPOUND INCLUDING SUBSTRATE FOR ENZYME AND RHODAMINE DYE; DRUG SCREENING FOR ANTICARCINOGENIC AGENTS | CYTOVIA, INC. | 2002-01-01 | — | — | US | disclosed |
| EP-1026988-A1 | NOVEL FLUORESCENT REPORTER MOLECULES AND THEIR APPLICATIONS INCLUDING ASSAYS FOR CASPASES | Cytovia, Inc. (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999018856-A1 | NOVEL FLUORESCENT REPORTER MOLECULES AND THEIR APPLICATIONS INCLUDING ASSAYS FOR CASPASES | CYTOVIA, INC. (US) | 1999-04-22 | — | — | WO | disclosed |