Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.42 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1926265 | 0.78 | PTPN1 (0.48) | SLC6A9PTPN1CNR1CNR2DCLRE1A | |
| SCHEMBL1927147 | 0.77 | PTPN1 (0.52) | SLC6A9PTPN1CNR1CNR2DCLRE1A | |
| SCHEMBL1926320 | 0.73 | PTPN1 (0.51) | SLC6A9PTPN1CNR1CNR2DCLRE1A | |
| SCHEMBL2595456 | 0.73 | CDC25B (0.47) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL27929241 | 0.71 | DCLRE1B (0.52) | SLC6A9PTPN1CNR1CNR2DCLRE1A | |
| SCHEMBL6489038 | 0.67 | MAPT (0.51) | PTPN1ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL27542931 | 0.67 | EGFR (0.52) | DCLRE1ADCLRE1BALDH1A1KDM4EMEN1 | |
| SCHEMBL92795 | 0.67 | MEN1 (0.54) | SLC6A9DCLRE1ADCLRE1BALDH1A1KDM4E | |
| SCHEMBL9517957 | 0.67 | MAPT (0.47) | PTPN1ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL15940350 | 0.67 | SLC6A9 (0.52) | SLC6A9PTPN1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763509-A1 | ALPHA-HELICAL MIMETICS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006002474-A1 | ALPHA-HELICAL MIMETICS | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2006-01-12 | — | — | WO | disclosed |