Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29046998 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL18751699 | 0.79 | TP53 (0.35) | — | |
| SCHEMBL19658176 | 0.79 | TP53 (0.35) | — | |
| SCHEMBL45664 | 0.78 | ALDH1A1 (0.34) | — | |
| SCHEMBL181744 | 0.78 | ALDH1A1 (0.34) | — | |
| SCHEMBL29047000 | 0.77 | ALDH1A1 (0.30) | — | |
| SCHEMBL11965242 | 0.76 | MGLL (0.31) | — | |
| SCHEMBL6033629 | 0.76 | KEAP1 (0.36) | KEAP1 | |
| SCHEMBL20848195 | 0.76 | MGLL (0.33) | — | |
| SCHEMBL18751705 | 0.76 | MGLL (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427744-B1 | A SYSTEM FOR ANTIBODY EXPRESSION AND ASSEMBLY | GENENTECH INC (US) | 2007-12-26 | — | — | EP | disclosed |
| US-5395924-A | Oligosaccharide or glycopeptide bound to lectin and conjugated with cell binding agent, improved targeting of cells for cytolysis | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1995-03-07 | — | — | US | disclosed |
| US-5239062-A | Blocked lectins, methods and affinity support for making same using affinity ligands, and method of killing selected cell populations having reduced nonselective cytotoxicity | DANA-FARBER CANCER INSTITUTE, INC. (US) | 1993-08-24 | — | — | US | disclosed |