SCHEMBL181744

SCHEMBL181744

O=C1C=CC(=O)N1C[C@H]1CC[C@H](C(=O)ON2C(=O)CCC2=O)CC1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
CYP1A2 P05177 1/20 0.34
HPGD P15428 1/20 0.34
CYP2C19 P33261 1/20 0.34
BLM P54132 1/20 0.34
WRN Q14191 1/20 0.34
HIF1A Q16665 1/20 0.34
LMNA P02545 1/20 0.31
GSK3A P49840 1/20 0.30
GSK3B P49841 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL45664 1.00 ALDH1A1 (0.34) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL28102949 0.95 BACE1 (0.36) ALDH1A1CYP1A2HPGDCYP2C19BLM
Carbimide SCHEMBL28226102 0.94 ALDH1A1 (0.31) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL4965543 0.91 ALDH1A1 (0.31) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL5578691 0.91 ALDH1A1 (0.31) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL28349186 0.91 ALDH1A1 (0.31) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL22650155 0.90 ALDH1A1 (0.37) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL28090625 0.88
SCHEMBL16552323 0.88 HTR1A (0.33) LMNAMGLL
SCHEMBL9892471 0.88 HTR1A (0.33) LMNAMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 650 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388619-A1 VERSATILE SYNTHETIC ROUTE FOR NEUTRAL MORPHOLINO OLIGONUCLEOTIDES WITH PHOSPHORYL GUANIDINIUM (PG) BACKBONE BIO SYNTHESIS INC (US) 2025-12-25 US claimed
WO-2024227424-A9 ANTIGEN-BINDING PROTEIN FOR HCLDN6 AND USE THEREOF 泰诚思(上海)生物医药有限公司 2025-02-20 WO claimed
WO-2024227426-A1 ANTIGEN-BINDING PROTEIN FOR HROR1 AND USE THEREOF 泰诚思(上海)生物医药有限公司 2024-11-07 WO claimed
WO-2024227424-A1 ANTIGEN-BINDING PROTEIN FOR HCLDN6 AND USE THEREOF 泰诚思(上海)生物医药有限公司 2024-11-07 WO claimed
US-12121527-B2 Anthracycline-based antibody drug conjugates having high in vivo tolerability NBE-THERAPEUTICS AG (CH) 2024-10-22 US claimed
US-20240150712-A1 ARTIFICIAL TARGET FOR ANTIGEN-SPECIFIC ACTIVATION AND EXPANSION OF CAR T CELLS MILTENYI BIOTEC B.V. & CO KG (DE) 2024-05-09 US claimed
US-20230285579-A1 NUCLEIC ACID LIGAND CONJUGATES AND USE THEREOF FOR DELIVERY TO CELLS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2023-09-14 US claimed
US-11332880-B2 Modifying natural feathers for use in sporting goods DURABIRD (US) 2022-05-17 US claimed
US-20210023103-A1 ANTHRACYCLINE-BASED ANTIBODY DRUG CONJUGATES HAVING HIGH IN VIVO TOLERABILITY NBE-THERAPEUTICS AG (CH) 2021-01-28 US claimed
US-10758556-B2 Anthracycline-based antibody drug conjugates having high in vivo tolerability NBE-THERAPEUTICS AG (CH) 2020-09-01 US claimed
US-20080311674-A1 METHODS AND COMPOSITIONS FOR ANALYZING PROTEINS MONOGRAM BIOSCIENCES, INC. (US) 2008-12-18 US claimed
US-20080199903-A1 Biological indicator STERIS INC. (US) 2008-08-21 US claimed
EP-1886143-A1 BIOLOGICAL INDICATOR Steris, Inc. (US) 2008-02-13 EP claimed
WO-2007046865-A1 BIOLOGICAL INDICATOR STERIS, INC. (US) 2007-04-26 WO claimed
US-20060269983-A1 Biological indicator AMERICAN STERILIZER COMPANY 2006-11-30 US claimed
US-20060134694-A1 Methods of protein profiling by thiolation INTEL CORPORATION (US) 2006-06-22 US claimed
US-20030013126-A1 Methods and compositions for analyzing proteins MONOGRAM BIOSCIENCES, INC. 2003-01-16 US claimed
US-20020197649-A1 Catalytic amplification of multiplexed assay signals MONOGRAM BIOSCIENCES, INC. 2002-12-26 US claimed
WO-2002097112-A2 CATALYTIC AMPLIFICATION OF MULTIPLEXED ASSAY SIGNALS ACLARA BIOSCIENCES, INC. (US) 2002-12-05 WO claimed
US-20020132990-A1 Bioengineered vehicles for targeted nucleic acid delivery DANA-FARBER CANCER INSTITUTE, INC. 2002-09-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388619-A1 VERSATILE SYNTHETIC ROUTE FOR NEUTRAL MORPHOLINO OLIGONUCLEOTIDES WITH PHOSPHORYL GUANIDINIUM (PG) BACKBONE RNMT, ADAR, RNGTT ALDH1A1 4823/4885CYP1A2 4877/4885HPGD 4863/4885
US-12121527-B2 Anthracycline-based antibody drug conjugates having high in vivo tolerability FCGR2A, FCGR3B, FCGR1A ALDH1A1 191/4885CYP1A2 640/4885HPGD 2275/4885
US-20210023103-A1 ANTHRACYCLINE-BASED ANTIBODY DRUG CONJUGATES HAVING HIGH IN VIVO TOLERABILITY FCGR2A, FCGR3B, FCGR1A ALDH1A1 191/4885CYP1A2 640/4885HPGD 2275/4885
US-10758556-B2 Anthracycline-based antibody drug conjugates having high in vivo tolerability FCGR2A, FCGR3B, FCGR1A ALDH1A1 191/4885CYP1A2 640/4885HPGD 2275/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.