SCHEMBL5493077

SCHEMBL5493077

O=C(O)CCCCCc1cccc(O)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 2/20 0.69
MAPT P10636 1/20 0.68
RXFP1 Q9HBX9 1/20 0.68
MGLL Q99685 1/20 0.58
HDAC3 O15379 1/20 0.56
MAPK1 P28482 1/20 0.56
ADRA1A P35348 1/20 0.56
HDAC4 P56524 1/20 0.56
SLC6A3 Q01959 1/20 0.56
HDAC1 Q13547 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC2 Q92769 1/20 0.56
HDAC10 Q969S8 1/20 0.56
HDAC11 Q96DB2 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
HDAC9 Q9UKV0 1/20 0.56
HDAC5 Q9UQL6 1/20 0.56
TBXAS1 P24557 6/20 0.55
CBS P35520 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7740301 1.00 HDAC6 (0.69) HDAC6MAPTRXFP1MGLLHDAC3
SCHEMBL1049248 0.98 HDAC6 (0.67) HDAC6MAPTRXFP1MGLLHDAC3
SCHEMBL30303107 0.98 HDAC6 (0.67) HDAC6MAPTRXFP1MGLLHDAC3
SCHEMBL3717612 0.93 HDAC6 (0.66) HDAC6MAPTRXFP1MGLLHDAC3
Stearic Acid SCHEMBL28392303 0.92 HDAC6 (0.61) HDAC6MAPTRXFP1MGLL
SCHEMBL18644325 0.91 HDAC6 (0.59) HDAC6MAPTRXFP1MGLLHDAC3
SCHEMBL1197247 0.89 MAPT (0.78) HDAC6MAPTRXFP1HDAC3MAPK1
SCHEMBL29563859 0.85 KEAP1 (0.63) HDAC6
SCHEMBL65250 0.85 KEAP1 (0.63) HDAC6
SCHEMBL31336237 0.85 KEAP1 (0.63) HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2886643-A1 PRODUCTION OF BIOPLASTICS Neol Biosolutions S.A. (ES) 2015-06-24 EP disclosed
EP-1118629-B1 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KK (JP) 2007-04-25 EP disclosed
US-20030180899-A1 Process for producing polyhydroxyalkanoates by utilizing microorganisms HONMA TSUTOMU (JP) 2003-09-25 US disclosed
US-6521429-B2 Using culture media and yeast extracts CANON KABUSHIKI KAISHA (JP) 2003-02-18 US disclosed
US-20010029039-A1 Polyhydroxyalkanoates and method of producing them by utilizing mircroorganisms CANON KABUSHIKI KAISHA (JP) 2001-10-11 US disclosed
EP-1118629-A2 Polyhydroxyalkanoates and method of producing them by utilizing microorganisms CANON KABUSHIKI KAISHA (JP) 2001-07-25 EP disclosed