Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.54 |
| ▸ | PREP | P48147 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5117593 | 0.84 | ACE (0.55) | ACEPREPDPP4RAB9AATM | |
| Telmesteine SCHEMBL1425417 | 0.80 | ACE (0.53) | ACEPREPRAB9AATM | |
| Telmesteine SCHEMBL637246 | 0.80 | ACE (0.53) | ACEPREPRAB9AATM | |
| SCHEMBL6706811 | 0.73 | ACE (0.47) | ACEPREPRAB9AATM | |
| SCHEMBL19084116 | 0.73 | ACE (0.55) | ACEPREPDPP4DPP8DPP7 | |
| SCHEMBL6051964 | 0.73 | ACE (0.55) | ACEPREPDPP4DPP8DPP7 | |
| SCHEMBL202300 | 0.72 | ACE (0.48) | ACEPREPATMHSD17B10 | |
| SCHEMBL202301 | 0.72 | ACE (0.48) | ACEPREPATMHSD17B10 | |
| SCHEMBL1022969 | 0.72 | ACE (0.48) | ACEPREPATMHSD17B10 | |
| SCHEMBL6482583 | 0.71 | ACE (0.57) | ACEPREPDPP4RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844022-A1 | QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF | Hanmi Pharm. Co., Ltd. (KR) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006071017-A1 | QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF | HANMI PHARM. CO., LTD. (KR) | 2006-07-06 | — | — | WO | disclosed |