SCHEMBL5494345

SCHEMBL5494345

S=C(c1nc[nH]n1)c1nc[nH]n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1636663 0.80
SCHEMBL9663668 0.74 P2RX7 (0.30)
SCHEMBL2241163 0.74
SCHEMBL19281540 0.73 GDA (0.31)
SCHEMBL381885 0.70
SCHEMBL14896369 0.70
SCHEMBL5003469 0.70
SCHEMBL6243277 0.70
SCHEMBL3212184 0.70
SCHEMBL9792948 0.69 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3558962-A1 NITRONE HERBICIDES FMC Corporation (US) 2019-10-30 EP disclosed
WO-2018118384-A1 NITRONE HERBICIDES FMC CORPORATION (US) 2018-06-28 WO disclosed
EP-1390056-A4 GLYCOPEPTIDE ANTIBIOTICS WYETH CORP (US) 2007-06-20 EP disclosed
EP-1390521-A4 GLYCOPEPTIDE ANTIBIOTICS WYETH CORP (US) 2006-11-15 EP disclosed
EP-1390521-A1 GLYCOPEPTIDE ANTIBIOTICS Wyeth Holdings Corporation (US) 2004-02-25 EP disclosed
EP-1390056-A2 GLYCOPEPTIDE ANTIBIOTICS Wyeth Holdings Corporation (US) 2004-02-25 EP disclosed
WO-2002086141-A1 GLYCOPEPTIDE ANTIBIOTICS WYETH HOLDINGS CORPORATION (US) 2002-10-31 WO disclosed
WO-2002085307-A2 GLYCOPEPTIDE ANTIBIOTICS WYETH HOLDINGS CORPORATION (US) 2002-10-31 WO disclosed
EP-1140913-A1 THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2001-10-10 EP disclosed
WO-2000034269-A1 THIOUREA INHIBITORS OF HERPES VIRUSES AMERICAN HOME PRODUCTS CORPORATION (US) 2000-06-15 WO disclosed
US-4617300-A BACTERICIDES SCHERING CORPORATION (US) 1986-10-14 US disclosed