Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 4/20 | 0.64 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.64 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.64 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.64 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.64 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.64 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.64 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.64 |
| ▸ | CPN1 | P15169 | 3/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8131617 | 0.92 | GABRA5 (0.60) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| SCHEMBL44579 | 0.91 | GABRA5 (0.75) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| Hydrochloric Acid SCHEMBL1967312 | 0.89 | GABRA5 (0.72) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| SCHEMBL17275233 | 0.85 | SLC6A12 (0.67) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| SCHEMBL18828823 | 0.83 | SLC6A1 (0.77) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| SCHEMBL1225755 | 0.83 | SLC6A1 (0.77) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| SCHEMBL18828784 | 0.83 | SLC6A1 (0.77) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| SCHEMBL9820766 | 0.82 | SLC6A12 (0.54) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| Hydrochloric Acid SCHEMBL5050450 | 0.82 | SLC6A1 (0.74) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 | |
| Hydrochloric Acid SCHEMBL22323200 | 0.82 | SLC6A1 (0.74) | SLC6A1GABRA5GABRB2SLC6A11SLC6A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104619709-A | Imidazopyridine derivatives as modulators of TNF activity | UCB PHARMA SA | 2015-05-13 | — | — | CN | disclosed |
| US-20070238721-A1 | Highly Selective Novel Amidation Method | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-10-11 | — | — | US | disclosed |
| EP-1753752-A1 | HIGHLY SELECTIVE NOVEL AMIDATION METHOD | Takeda Pharmaceutical Company Limited (JP) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005121133-A1 | HIGHLY SELECTIVE NOVEL AMIDATION METHOD | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238721-A1 | Highly Selective Novel Amidation Method | NAAA, CPS1, COASY | SLC6A1 3877/4885GABRA5 2173/4885GABRB2 2186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.