Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6632635 | 0.98 | TSHR (0.38) | TSHRALDH1A1KDM4ETDP1 | |
| SCHEMBL1809020 | 0.94 | TSHR (0.38) | TSHRALDH1A1KDM4ETDP1 | |
| SCHEMBL7534039 | 0.75 | BRD4 (0.33) | TSHRTDP1 | |
| SCHEMBL19011596 | 0.71 | — | — | |
| SCHEMBL181531 | 0.65 | TSHR (0.35) | TSHRALDH1A1TDP1 | |
| SCHEMBL19858947 | 0.64 | TDP1 (0.32) | TSHRTDP1 | |
| SCHEMBL11363682 | 0.64 | TSHR (0.34) | TSHRTDP1 | |
| SCHEMBL10436985 | 0.64 | ALDH1A1 (0.49) | ALDH1A1KDM4EGAAHPGDHSD17B10 | |
| SCHEMBL9838534 | 0.63 | MEN1 (0.35) | TSHRTDP1 | |
| SCHEMBL29290644 | 0.62 | KMT2A (0.57) | TSHRALDH1A1KDM4ETDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262163-B2 | Short amphipathic peptides with activity against bacteria and intracellular pathogens | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2007-08-28 | — | — | US | disclosed |
| US-20040059088-A1 | Short amphipathic peptides with activity against bacteria and intracellular pathogens | MCLAUGHLIN MARK L (US) | 2004-03-25 | — | — | US | disclosed |
| US-6566334-B1 | For therapy of bacterial infection | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2003-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059088-A1 | Short amphipathic peptides with activity against bacteria and intracellular pathogens | VIP, MDK, HM13 | TSHR 3436/4885ALDH1A1 4846/4885KDM4E 4672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.