SCHEMBL5496697

SCHEMBL5496697

CCCCCCCCCC[Si](OC)(OC)OC.Cl[Si](Cl)(Cl)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
KCNH2 Q12809 2/20 0.36
NAAA Q02083 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
MPO P05164 1/20 0.33
LTA4H P09960 1/20 0.33
CYP19A1 P11511 3/20 0.33
PPARA Q07869 1/20 0.33
EPHX1 P07099 3/20 0.33
EPHX2 P34913 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33
MLNR O43193 1/20 0.33
NR1I2 O75469 1/20 0.33
ESR1 P03372 1/20 0.33
NR3C1 P04150 1/20 0.33
PGR P06401 1/20 0.33
ADRB2 P07550 1/20 0.33
CHRM2 P08172 1/20 0.33
ADRB1 P08588 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17969228 0.85 LMNA (0.45) LMNAKCNH2NAAAMPOLTA4H
SCHEMBL5545345 0.83 KCNH2 (0.40) KCNH2NAAACYP19A1EPHX1EPHX2
Toluene SCHEMBL16859706 0.81 LMNA (0.47) LMNAKCNH2NAAAMPOLTA4H
SCHEMBL20574355 0.81 LMNA (0.41) LMNAKCNH2NAAAMPOLTA4H
SCHEMBL18108287 0.80 KCNH2 (0.38) KCNH2NAAAZDHHC2LTA4HCYP19A1
SCHEMBL18108007 0.80 KCNH2 (0.38) KCNH2NAAAZDHHC2LTA4HCYP19A1
O-Xylene SCHEMBL8570881 0.80 LMNA (0.49) LMNAKCNH2NAAAMPOALDH1A1
SCHEMBL5396830 0.78 LMNA (0.40) LMNAMPOLTA4HEPHX2ALDH1A1
SCHEMBL28903600 0.77 LMNA (0.53) LMNAKCNH2
SCHEMBL25395317 0.77 LTA4H (0.42) LMNAKCNH2NAAAZDHHC2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070082291-A1 Lithographic Printing Plate Precursor and Lithographic Printing Method FUJI PHOTO FILM CO., LTD. (JP) 2007-04-12 US disclosed