SCHEMBL5396830

SCHEMBL5396830

CCCC[Si](OC)(OC)OC.CO[Si](OC)(OC)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
LTA4H P09960 2/20 0.34
MPO P05164 2/20 0.33
POLB P06746 1/20 0.32
EPHX2 P34913 1/20 0.32
TSHR P16473 1/20 0.32
CA4 P22748 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
ALOX12 P18054 1/20 0.31
CRHBP P24387 1/20 0.31
HTT P42858 1/20 0.31
CRHR2 Q13324 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
PCSK9 Q8NBP7 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17969228 0.93 LMNA (0.45) LMNALTA4HMPOEPHX2HTT
SCHEMBL6752944 0.88 LMNA (0.37) LMNALTA4HMPO
Benzene SCHEMBL27743707 0.82 LMNA (0.52) LMNALTA4HMPOTSHR
SCHEMBL20574355 0.82 LMNA (0.41) LMNALTA4HMPOEPHX2HTT
Aniline SCHEMBL2117721 0.80 TSHR (0.41) LMNALTA4HMPOTSHRMAPT
Diphenylether SCHEMBL9580832 0.80 LTA4H (0.56) LMNALTA4HPOLBTSHRCA4
SCHEMBL5496697 0.78 LMNA (0.44) LMNALTA4HMPOEPHX2HTT
SCHEMBL37986 0.78 CA4 (0.41) LMNALTA4HPOLBTSHRCA4
SCHEMBL20954192 0.78 CHRM2 (0.40) TSHR
Alcohol SCHEMBL4340926 0.77 ESR1 (0.35) LMNAPOLBTSHRCA4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7211522-B2 Method of forming thick silica-based film NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2007-05-01 US disclosed