SCHEMBL5496900

SCHEMBL5496900

B(Oc1cccc2c1Cc1ccccc1-2)Oc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.47
RAB9A P51151 4/20 0.41
NPC1 O15118 3/20 0.41
HTR7 P34969 1/20 0.39
HTR2B P41595 1/20 0.39
MAOA P21397 1/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA4 P22748 2/20 0.36
CA6 P23280 2/20 0.36
MAP3K9 P80192 1/20 0.36
MAP3K11 Q16584 1/20 0.36
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15096689 0.86 PNMT (0.45) PNMTRAB9ANPC1HTR7HTR2B
SCHEMBL29693310 0.86 PNMT (0.45) PNMTRAB9ANPC1HTR7HTR2B
SCHEMBL28832018 0.82 PNMT (0.52) PNMTRAB9ANPC1HTR7HTR2B
SCHEMBL7869026 0.80 ALDH1A1 (0.40) PNMTRAB9ANPC1KDM4EALDH1A1
SCHEMBL29090327 0.79 PNMT (0.49) PNMTRAB9ANPC1HTR7HTR2B
SCHEMBL8854649 0.79 DRD2 (0.54) PNMTRAB9ANPC1CA1CA2
SCHEMBL15141606 0.79 PNMT (0.49) PNMTRAB9ANPC1HTR7HTR2B
SCHEMBL524602 0.77 PNMT (0.63) PNMTRAB9ANPC1HTR7HTR2B
SCHEMBL30103334 0.77 PNMT (0.63) PNMTRAB9ANPC1HTR7HTR2B
SCHEMBL21951946 0.76 PNMT (0.50) PNMTRAB9ANPC1HTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504771-A Spiropyran derivative with color and fluorescence dual switch, photochromic material, and preparation method and application thereof 安徽省东超科技有限公司 2025-02-25 CN claimed
CN-118878402-A Preparation method of trifluoromethyl ketone compound based on palladium catalysis of C-N bond cleavage 大连理工大学 2024-11-01 CN claimed
EP-1425168-A4 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS UNIV ROCHESTER (US) 2007-01-03 EP claimed
EP-1425168-A2 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS University of Rochester (US) 2004-06-09 EP claimed
US-20030039838-A1 Light-emitting organic oligomer compositions UNIVERSITY OF ROCHESTER 2003-02-27 US claimed
WO-2003008475-A2 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS UNIVERSITY OF ROCHESTER (US) 2003-01-30 WO claimed
CN-119504771-A Spiropyran derivative with color and fluorescence dual switch, photochromic material, and preparation method and application thereof 安徽省东超科技有限公司 2025-02-25 CN disclosed
EP-1425168-A4 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS UNIV ROCHESTER (US) 2007-01-03 EP disclosed
US-7057009-B2 Crosslinking polyfluorene; molecular orientation UNIVERSITY OF ROCHESTER (US) 2006-06-06 US disclosed
EP-1425168-A2 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS University of Rochester (US) 2004-06-09 EP disclosed
US-20030039838-A1 Light-emitting organic oligomer compositions UNIVERSITY OF ROCHESTER 2003-02-27 US disclosed
WO-2003008475-A2 LIGHT-EMITTING ORGANIC OLIGOMER COMPOSITIONS UNIVERSITY OF ROCHESTER (US) 2003-01-30 WO disclosed