Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.36 |
| ▸ | LTA4H | P09960 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5496900 | 0.80 | PNMT (0.47) | ALDH1A1RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL729697 | 0.77 | PTGS1 (0.51) | ALDH1A1RAB9ASMN1; SMN2NPC1PTGS1 | |
| SCHEMBL7869027 | 0.73 | SMN1; SMN2 (0.37) | ALDH1A1RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL2139179 | 0.72 | KDM4E (0.54) | ALDH1A1RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL15096689 | 0.69 | PNMT (0.45) | ALDH1A1RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL29693310 | 0.69 | PNMT (0.45) | ALDH1A1RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL15141606 | 0.67 | PNMT (0.49) | ALDH1A1RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL28832018 | 0.66 | PNMT (0.52) | ALDH1A1RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL1272400 | 0.65 | PTGS1 (0.49) | ALDH1A1RAB9ASMN1; SMN2MEN1NPC1 | |
| SCHEMBL8854649 | 0.64 | DRD2 (0.54) | ALDH1A1RAB9ASMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300502-B1 | Multi-armed chromophores with very large two-photon absorption cross-sections | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2001-10-09 | — | — | US | disclosed |
| US-6100405-A | Benzothiazole-containing two-photon chromophores exhibiting strong frequency upconversion | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2000-08-08 | — | — | US | disclosed |