Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 9/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28743205 | 0.85 | ALDH1A1 (0.44) | KCNA5EPHX2TBXAS1LMNATDP1 | |
| SCHEMBL8461392 | 0.81 | CYP1A2 (0.49) | KCNA5TBXAS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10512019 | 0.81 | CYP1A2 (0.49) | KCNA5TBXAS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4205851 | 0.81 | KCNA5 (0.45) | KCNA5EPHX2TBXAS1CYP1A2CYP3A4 | |
| SCHEMBL10424313 | 0.80 | LTB4R (0.50) | SMN1; SMN2 | |
| SCHEMBL9826864 | 0.80 | TBXAS1 (0.53) | TBXAS1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9826871 | 0.80 | TBXAS1 (0.53) | TBXAS1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6178344 | 0.78 | CYP1A2 (0.51) | KCNA5TBXAS1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8503461 | 0.77 | TBXAS1 (0.59) | TBXAS1TDP1 | |
| SCHEMBL22775934 | 0.77 | CYP1A2 (0.50) | KCNA5TBXAS1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856063-A1 | 5-PHENYL-PENTANOIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS FOR THE TREATMENT OF ASTHMA AND OTHER DISEASES | Ranbaxy Laboratories Limited (IN) | 2007-11-21 | — | — | EP | claimed |
| WO-2006090235-A1 | 5-PHENYL-PENTANOIC ACID DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS FOR THE TREATMENT OF ASTHMA AND OTHER DISEASES | RANBAXY LABORATORIES LIMITED (IN) | 2006-08-31 | — | — | WO | claimed |