Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.55 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826537 | 0.83 | ALOX15 (0.72) | ALOX15TRPV1KDM4EMEN1HPGD | |
| SCHEMBL10606316 | 0.82 | MAPT (0.56) | KAT8ALOX15TMPRSS4MEN1HTT | |
| SCHEMBL24539597 | 0.81 | TRPV1 (0.58) | ALOX15TRPV1PPARAKDM4EMEN1 | |
| SCHEMBL21332089 | 0.81 | KAT8 (0.71) | KAT8TRPV1PPARAKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL10386190 | 0.80 | ALOX15 (0.55) | KAT8ALOX15 | |
| SCHEMBL1079224 | 0.80 | KAT8 (0.97) | KAT8PPARAEGFR | |
| SCHEMBL11517335 | 0.80 | KAT8 (0.74) | KAT8ALOX15PPARAKDM4ELMNA | |
| SCHEMBL10607741 | 0.80 | P2RX1 (0.63) | TMPRSS4MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL6283982 | 0.79 | HNF4A (0.67) | ALOX15TMPRSS4KDM4EMEN1HPGD | |
| SCHEMBL8531761 | 0.79 | KAT8 (0.77) | KAT8TRPV1PPARAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0628302-A2 | Oral composition containing salicylanilide antibacterial agent | Colgate-Palmolive Company (US) | 1994-12-14 | — | — | EP | claimed |
| US-5275805-A | Inhibitors of plaque in mouths with mixtures of salicylanilide and nonionic surfactants | COLGATE-PALMOLIVE CO. | 1994-01-04 | — | — | US | claimed |
| EP-0038191-B1 | 5-ACYLSALICYLANILIDES DERIVATIVES AND METHOD FOR INHIBITING THE GROWTH OF MICROORGANISMS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1984-07-25 | — | — | EP | claimed |
| EP-1328507-B1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | UNIV NEW YORK STATE RES FOUND (US) | 2007-03-14 | — | — | EP | disclosed |
| EP-1328507-A1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | The Research Foundation Of State University of New York (US) | 2003-07-23 | — | — | EP | disclosed |
| US-6407288-B1 | AS ANTIBACTERIAL AGAINST GRAM NEGATIVE AND GRAM POSITIVE BACTERIA AND AS ANTIINFLAMMATORY AGENTS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-06-18 | — | — | US | disclosed |
| US-20020065322-A1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE | 2002-05-30 | — | — | US | disclosed |
| WO-2002028819-A1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2002-04-11 | — | — | WO | disclosed |
| EP-0628302-A2 | Oral composition containing salicylanilide antibacterial agent | Colgate-Palmolive Company (US) | 1994-12-14 | — | — | EP | disclosed |
| US-5275805-A | Inhibitors of plaque in mouths with mixtures of salicylanilide and nonionic surfactants | COLGATE-PALMOLIVE CO. | 1994-01-04 | — | — | US | disclosed |
| EP-0221211-B1 | USE OF SECONDARY AMIDE COMPOUNDS FOR THE MANUFACTURE OF MEDICAMENTS FOR THE TREATMENT OF DERMATOLOGICAL INFLAMMATION | UNILEVER PLC (GB) | 1989-01-11 | — | — | EP | disclosed |
| EP-0221211-A1 | Use of secondary amide compounds for the manufacture of medicaments for the treatment of dermatological inflammation | UNILEVER PLC (GB) | 1987-05-13 | — | — | EP | disclosed |
| US-4560549-A | TOPICAL AND SYSTEMICAL; HUMANS ANIMALS; MICROBIOCIDES | LEVER BROTHERS COMPANY (US) | 1985-12-24 | — | — | US | disclosed |
| EP-0038191-B1 | 5-ACYLSALICYLANILIDES DERIVATIVES AND METHOD FOR INHIBITING THE GROWTH OF MICROORGANISMS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1984-07-25 | — | — | EP | disclosed |
| EP-0038191-B1 | 5-ACYLSALICYLANILIDES DERIVATIVES AND METHOD FOR INHIBITING THE GROWTH OF MICROORGANISMS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1984-07-25 | — | — | EP | disclosed |
| EP-0038191-A1 | 5-Acylsalicylanilides derivatives and method for inhibiting the growth of microorganisms | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1981-10-21 | — | — | EP | disclosed |
| EP-0038191-A1 | 5-Acylsalicylanilides derivatives and method for inhibiting the growth of microorganisms | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1981-10-21 | — | — | EP | disclosed |
| EP-0038191-A1 | 5-Acylsalicylanilides derivatives and method for inhibiting the growth of microorganisms | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1981-10-21 | — | — | EP | disclosed |
| US-4287191-A | Novel salicylanilides and microbiocidal compositions and uses thereof | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1981-09-01 | — | — | US | disclosed |
| US-4287191-A | Novel salicylanilides and microbiocidal compositions and uses thereof | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1981-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065322-A1 | NAPHTHYLSALICYLANILIDES AS ANTIMICROBIAL AND ANTIINFLAMMATORY AGENTS | PTGES3, FPR3, PTGS1 | KAT8 3258/4885ALOX15 31/4885TRPV1 1343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.