Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA6 | P08185 | 4/20 | 0.80 |
| ▸ | FNTA | P49354 | 1/20 | 0.69 |
| ▸ | FNTB | P49356 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | SHBG | P04278 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15904593 | 0.89 | SERPINA6 (1.00) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL14525642 | 0.89 | SERPINA6 (1.00) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL14420894 | 0.89 | SERPINA6 (1.00) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL668966 | 0.89 | SERPINA6 (1.00) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL15920543 | 0.89 | SERPINA6 (1.00) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL9348241 | 0.88 | SERPINA6 (0.85) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL9348234 | 0.88 | SERPINA6 (0.85) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL18927106 | 0.88 | SERPINA6 (0.85) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL6347180 | 0.87 | SERPINA6 (0.84) | SERPINA6FNTAFNTBSMN1; SMN2LMNA | |
| SCHEMBL31095098 | 0.86 | SERPINA6 (0.82) | SERPINA6FNTAFNTBSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115725522-A | Steroid hormone dehydrogenase, gene, mutant, construction method and application | 湖南新合新生物医药有限公司 | 2023-03-03 | — | — | CN | claimed |
| CN-113528474-B | 3-sterone-delta1Dehydrogenase and coding gene and application thereof | 中国科学院天津工业生物技术研究所 | 2021-12-10 | — | — | CN | claimed |
| CN-111349677-B | Biocatalysis preparation method of steroid C1, 2-position dehydrogenation drug intermediate | 中国科学院天津工业生物技术研究所 | 2021-11-12 | — | — | CN | claimed |
| CN-113528474-A | 3-sterone-delta1Dehydrogenase and coding gene and application thereof | 中国科学院天津工业生物技术研究所 | 2021-10-22 | — | — | CN | claimed |
| CN-111349677-A | Biocatalysis preparation method of steroid C1, 2-position dehydrogenation drug intermediate | 中国科学院天津工业生物技术研究所 | 2020-06-30 | — | — | CN | claimed |
| CN-115725522-A | Steroid hormone dehydrogenase, gene, mutant, construction method and application | 湖南新合新生物医药有限公司 | 2023-03-03 | — | — | CN | disclosed |
| CN-113528474-B | 3-sterone-delta1Dehydrogenase and coding gene and application thereof | 中国科学院天津工业生物技术研究所 | 2021-12-10 | — | — | CN | disclosed |
| CN-111349677-B | Biocatalysis preparation method of steroid C1, 2-position dehydrogenation drug intermediate | 中国科学院天津工业生物技术研究所 | 2021-11-12 | — | — | CN | disclosed |
| CN-113528474-A | 3-sterone-delta1Dehydrogenase and coding gene and application thereof | 中国科学院天津工业生物技术研究所 | 2021-10-22 | — | — | CN | disclosed |
| CN-113493484-A | Preparation method of methylprednisolone and intermediate thereof | 河南利华制药有限公司 | 2021-10-12 | — | — | CN | disclosed |
| CN-113423827-A | Biotechnological optimization of microorganisms for 1, 2-dehydrogenation of steroids | 赛诺菲 | 2021-09-21 | — | — | CN | disclosed |
| CN-111349677-A | Biocatalysis preparation method of steroid C1, 2-position dehydrogenation drug intermediate | 中国科学院天津工业生物技术研究所 | 2020-06-30 | — | — | CN | disclosed |
| CN-110612122-A | Methods and compositions related to combination therapy with anti-inflammatory agents and synthetic nanocarriers comprising immunosuppressants | 西莱克塔生物科技公司 | 2019-12-24 | — | — | CN | disclosed |
| US-20070129282-A1 | Pharmaceutical treatments and compositions | BIOVIE INC. | 2007-06-07 | — | — | US | disclosed |
| US-5001116-A | Inhibition of angiogenesis | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0088462-A2 | Anti-inflammatory and rheumatic composition containing organophosphonate and steroid | THE PROCTER & GAMBLE COMPANY (US) | 1983-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129282-A1 | Pharmaceutical treatments and compositions | HSD3B1, HSD3B2, HSD17B1 | SERPINA6 87/4885FNTA 382/4885FNTB 921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.